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Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Transmission Dynamics and Immune Responses in a Household of Vaccinated Persons
While SARS-CoV-2 vaccines prevent severe disease effectively, postvaccination “breakthrough” COVID-19 infections and transmission among vaccinated individuals remain ongoing concerns. We present an in-depth characterization of transmission and immunity among vaccinated individuals in a household, re...
| Autores principales: | , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807302/ https://www.ncbi.nlm.nih.gov/pubmed/35037050 http://dx.doi.org/10.1093/cid/ciac029 |
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| author | Liu, Jamin Laurie, Matthew T Rubio, Luis Vazquez, Sara E Sunshine, Sara Mitchell, Anthea M Hapte-Selassie, Matthias Mann, Sabrina A Pilarowski, Genay Black, Douglas Marquez, Carina Rojas, Susana Lionakis, Michail S Petersen, Maya Whitman, Jeffrey D Jain, Vivek Anderson, Mark Havlir, Diane DeRisi, Joseph |
| author_facet | Liu, Jamin Laurie, Matthew T Rubio, Luis Vazquez, Sara E Sunshine, Sara Mitchell, Anthea M Hapte-Selassie, Matthias Mann, Sabrina A Pilarowski, Genay Black, Douglas Marquez, Carina Rojas, Susana Lionakis, Michail S Petersen, Maya Whitman, Jeffrey D Jain, Vivek Anderson, Mark Havlir, Diane DeRisi, Joseph |
| author_sort | Liu, Jamin |
| collection | PubMed |
| description | While SARS-CoV-2 vaccines prevent severe disease effectively, postvaccination “breakthrough” COVID-19 infections and transmission among vaccinated individuals remain ongoing concerns. We present an in-depth characterization of transmission and immunity among vaccinated individuals in a household, revealing complex dynamics and unappreciated comorbidities, including autoimmunity to type 1 interferon in the presumptive index case. |
| format | Online Article Text |
| id | pubmed-8807302 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2022 |
| publisher | Oxford University Press |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-88073022022-02-02 Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Transmission Dynamics and Immune Responses in a Household of Vaccinated Persons Liu, Jamin Laurie, Matthew T Rubio, Luis Vazquez, Sara E Sunshine, Sara Mitchell, Anthea M Hapte-Selassie, Matthias Mann, Sabrina A Pilarowski, Genay Black, Douglas Marquez, Carina Rojas, Susana Lionakis, Michail S Petersen, Maya Whitman, Jeffrey D Jain, Vivek Anderson, Mark Havlir, Diane DeRisi, Joseph Clin Infect Dis Brief Report While SARS-CoV-2 vaccines prevent severe disease effectively, postvaccination “breakthrough” COVID-19 infections and transmission among vaccinated individuals remain ongoing concerns. We present an in-depth characterization of transmission and immunity among vaccinated individuals in a household, revealing complex dynamics and unappreciated comorbidities, including autoimmunity to type 1 interferon in the presumptive index case. Oxford University Press 2022-01-17 /pmc/articles/PMC8807302/ /pubmed/35037050 http://dx.doi.org/10.1093/cid/ciac029 Text en © The Author(s) 2022. Published by Oxford University Press for the Infectious Diseases Society of America. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
| spellingShingle | Brief Report Liu, Jamin Laurie, Matthew T Rubio, Luis Vazquez, Sara E Sunshine, Sara Mitchell, Anthea M Hapte-Selassie, Matthias Mann, Sabrina A Pilarowski, Genay Black, Douglas Marquez, Carina Rojas, Susana Lionakis, Michail S Petersen, Maya Whitman, Jeffrey D Jain, Vivek Anderson, Mark Havlir, Diane DeRisi, Joseph Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Transmission Dynamics and Immune Responses in a Household of Vaccinated Persons |
| title | Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Transmission Dynamics and Immune Responses in a Household of Vaccinated Persons |
| title_full | Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Transmission Dynamics and Immune Responses in a Household of Vaccinated Persons |
| title_fullStr | Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Transmission Dynamics and Immune Responses in a Household of Vaccinated Persons |
| title_full_unstemmed | Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Transmission Dynamics and Immune Responses in a Household of Vaccinated Persons |
| title_short | Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Transmission Dynamics and Immune Responses in a Household of Vaccinated Persons |
| title_sort | severe acute respiratory syndrome coronavirus 2 (sars-cov-2) transmission dynamics and immune responses in a household of vaccinated persons |
| topic | Brief Report |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807302/ https://www.ncbi.nlm.nih.gov/pubmed/35037050 http://dx.doi.org/10.1093/cid/ciac029 |
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