Synthesis, Characterization, and in vivo Evaluation of a Novel Potent Autotaxin-Inhibitor

The autotaxin-lysophosphatidic acid (ATX-LPA) signaling pathway plays a role in a variety of autoimmune diseases, such as rheumatoid arthritis or neurodegeneration. A link to the pathogenesis of glaucoma is suggested by an overactive ATX-LPA axis in aqueous humor samples of glaucoma patients. Analys...

Descripción completa

Detalles Bibliográficos
Autores principales: Hunziker, Daniel, Reinehr, Sabrina, Palmhof, Marina, Wagner, Natalie, Biniasch, Thomas, Stute, Gesa, Mattei, Patrizio, Schmitz, Petra, DiGiorgio, Patrick, Hert, Jérôme, Rudolph, Markus G., Benz, Joerg, Stihle, Martine, Gsell, Bernard, Müller, Stephan, Gasser, Rodolfo, Schonhoven, Nina, Ullmer, Christoph, Joachim, Stephanie C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807399/
https://www.ncbi.nlm.nih.gov/pubmed/35126098
http://dx.doi.org/10.3389/fphar.2021.699535

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807399/
https://www.ncbi.nlm.nih.gov/pubmed/35126098
http://dx.doi.org/10.3389/fphar.2021.699535

Ejemplares similares