Cargando…

Nanobodies Are Potential Therapeutic Agents for the Ebola Virus Infection

Ebola fever is an acute, highly contagious viral disease with a mortality rate that can reach 90%. There are currently no licensed therapeutic agents specific to Ebola in the world. Monoclonal antibodies (MAbs) with viral-neutralizing activity and high specificity to the Ebola virus glycoprotein (EB...

Descripción completa

Detalles Bibliográficos
Autores principales:	Esmagambetov, I. B., Shcheblyakov, D. V., Egorova, D. A., Voronina, O. L., Derkaev, A. A., Voronina, D. V., Popova, O., Ryabova, E. I., Shcherbinin, D. N., Aksenova, E. I., Semenov, A. N., Kunda, M. S., Ryzhova, N. N., Zubkova, O. V., Tukhvatulin, A. I., Logunov, D. Yu., Naroditsky, B. S., Borisevich, S. V., Gintsburg, A. L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	A.I. Gordeyev 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807537/ https://www.ncbi.nlm.nih.gov/pubmed/35127147 http://dx.doi.org/10.32607/actanaturae.11487

Ejemplares similares

Development of Neutralizing Nanobodies to the Hemagglutinin Stem Domain of Influenza A Viruses
por: Voronina, D. V., et al.
Publicado: (2021)

Single-Domain Antibodies Efficiently Neutralize SARS-CoV-2 Variants of Concern
por: Favorskaya, Irina A., et al.
Publicado: (2022)

Genetic Passive Immunization with Adenoviral Vector Expressing Chimeric Nanobody-Fc Molecules as Therapy for Genital Infection Caused by Mycoplasma hominis
por: Burmistrova, Daria A., et al.
Publicado: (2016)

Virus-Vectored Ebola Vaccines
por: Dolzhikova, I.V., et al.
Publicado: (2017)

rAAV expressing recombinant neutralizing antibody for the botulinum neurotoxin type A prophylaxis
por: Derkaev, Artem A., et al.
Publicado: (2022)

Immunogenicity of Different Forms of Middle East Respiratory Syndrome S Glycoprotein
por: Ozharovskaia, T. A., et al.
Publicado: (2019)

Toll-Like Receptors (TLRs): The Role in Tumor Progression
por: Shcheblyakov, D.V., et al.
Publicado: (2010)

Preclinical Studies of Immunogenity, Protectivity, and Safety of the Combined Vector Vaccine for Prevention of the Middle East Respiratory Syndrome
por: Dolzhikova, I. V., et al.
Publicado: (2020)

Burkholderia contaminans Biofilm Regulating Operon and Its Distribution in Bacterial Genomes
por: Voronina, Olga L., et al.
Publicado: (2016)

Mosaic structure of Mycobacterium bovis BCG genomes as a representation of phage sequences’ mobility
por: Voronina, Olga L., et al.
Publicado: (2016)

Cross-Reactive Fc-Fused Single-Domain Antibodies to Hemagglutinin Stem Region Protect Mice from Group 1 Influenza a Virus Infection
por: Voronina, Daria V., et al.
Publicado: (2022)

Camelid VHHs Fused to Human Fc Fragments Provide Long Term Protection Against Botulinum Neurotoxin A in Mice
por: Godakova, Svetlana A., et al.
Publicado: (2019)

Genetic Diversity of Listeria Detected in the Production Environment of Meat Processing
por: Voronina, O. L., et al.
Publicado: (2023)

The Characteristics of Ubiquitous and Unique Leptospira Strains from the Collection of Russian Centre for Leptospirosis
por: Voronina, Olga L., et al.
Publicado: (2014)

Construction of a pIX-modified Adenovirus Vector Able to Effectively Bind to Nanoantibodies for Targeting
por: Garas, M. N., et al.
Publicado: (2014)

The Variability of the Order Burkholderiales Representatives in the Healthcare Units
por: Voronina, Olga L., et al.
Publicado: (2015)

On Burkholderiales order microorganisms and cystic fibrosis in Russia
por: Voronina, Olga L., et al.
Publicado: (2018)

Safety and immunogenicity of an rAd26 and rAd5 vector-based heterologous prime-boost COVID-19 vaccine in two formulations: two open, non-randomised phase 1/2 studies from Russia
por: Logunov, Denis Y, et al.
Publicado: (2020)

Safety and efficacy of an rAd26 and rAd5 vector-based heterologous prime-boost COVID-19 vaccine: an interim analysis of a randomised controlled phase 3 trial in Russia
por: Logunov, Denis Y, et al.
Publicado: (2021)

An open, non-randomised, phase 1/2 trial on the safety, tolerability, and immunogenicity of single-dose vaccine “Sputnik Light” for prevention of coronavirus infection in healthy adults
por: Tukhvatulin, Amir I., et al.
Publicado: (2021)

rAAV expressing recombinant antibody for emergency prevention and long-term prophylaxis of COVID-19
por: Esmagambetov, Ilias B., et al.
Publicado: (2023)

Integrated into Environmental Biofilm Chromobacterium vaccinii Survives Winter with Support of Bacterial Community
por: Egorova, Daria A., et al.
Publicado: (2020)

Chlamydial Type III Secretion System Needle Protein Induces Protective Immunity against Chlamydia muridarum Intravaginal Infection
por: Koroleva, Ekaterina A., et al.
Publicado: (2017)

Protective Immune Response against Bacillus anthracis Induced by Intranasal Introduction of a Recombinant Adenovirus Expressing the Protective Antigen Fused to the Fc-fragment of IgG2a
por: Shcherbinin, D. N., et al.
Publicado: (2014)

Safety and immunogenicity of GamEvac-Combi, a heterologous VSV- and Ad5-vectored Ebola vaccine: An open phase I/II trial in healthy adults in Russia
por: Dolzhikova, I. V., et al.
Publicado: (2017)

Stimulation of Dectin-1 and Dectin-2 during Parenteral Immunization, but Not Mincle, Induces Secretory IgA in Intestinal Mucosa
por: Dzharullaeva, Alina S., et al.
Publicado: (2018)

A In Vitro and In Vivo Study of the Ability of NOD1 Ligands to Activate the Transcriptional Factor NF-kB
por: Tukhvatulin, A.I., et al.
Publicado: (2011)

Neutralizing Activity of Sera from Sputnik V-Vaccinated People against Variants of Concern (VOC: B.1.1.7, B.1.351, P.1, B.1.617.2, B.1.617.3) and Moscow Endemic SARS-CoV-2 Variants
por: Gushchin, Vladimir A., et al.
Publicado: (2021)

Single-domain antibody delivery using an mRNA platform protects against lethal doses of botulinum neurotoxin A
por: Panova, Eugenia A., et al.
Publicado: (2023)

Triggering of Toll-like Receptor-2 in Mouse Myelomonocytic Leukaemia Cells WEHI-3B Leads to the Suppression of Apoptosis and Promotes Tumor Progression in Vivo
por: Shcheblyakov, D.V., et al.
Publicado: (2011)

NOD1/2 and the C-Type Lectin Receptors Dectin-1 and Mincle Synergistically Enhance Proinflammatory Reactions Both In Vitro and In Vivo
por: Tukhvatulin, Amir I, et al.
Publicado: (2020)

Powerful Complex Immunoadjuvant Based on Synergistic Effect of Combined TLR4 and NOD2 Activation Significantly Enhances Magnitude of Humoral and Cellular Adaptive Immune Responses
por: Tukhvatulin, Amir I., et al.
Publicado: (2016)

Listeria monocytogenes ST37 Distribution in the Moscow Region and Properties of Clinical and Foodborne Isolates
por: Voronina, Olga L., et al.
Publicado: (2023)

Adjuvantation of an Influenza Hemagglutinin Antigen with TLR4 and NOD2 Agonists Encapsulated in Poly(D,L-Lactide-Co-Glycolide) Nanoparticles Enhances Immunogenicity and Protection against Lethal Influenza Virus Infection in Mice
por: Tukhvatulin, Amir, et al.
Publicado: (2020)

Porin from Marine Bacterium Marinomonas primoryensis KMM 3633(T): Isolation, Physico-Chemical Properties, and Functional Activity
por: Novikova, Olga D., et al.
Publicado: (2020)

Induction of a Protective Heterosubtypic Immune Response Against the Influenza Virus by using Recombinant Adenoviral Vectors Expressing Hemagglutinin of the Influenza H5 Virus
por: Shmarov, M.M., et al.
Publicado: (2010)

An Efficient Method for the Delivery of the Interleukin-2 Gene to Human Hematopoietic Cells using the  Fiber-Modified Recombinant Adenovirus
por: Rogozhin, V.N., et al.
Publicado: (2011)

Safety and immunogenicity of rAd26 and rAd5 vector-based heterologous prime-boost COVID-19 vaccine against SARS-CoV-2 in healthy adolescents: an open-label, non-randomized, multicenter, phase 1/2, dose-escalation study
por: Tukhvatulin, Amir I., et al.
Publicado: (2023)

Vaccination potential of B and T epitope-enriched NP and M2 against Influenza A viruses from different clades and hosts
por: Tutykhina, Irina, et al.
Publicado: (2018)

Recombinant Influenza Vaccines
por: Sedova, E.S., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_cpglt250m6a91o0qu588oi0kbh