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FGFC1 Selectively Inhibits Erlotinib-Resistant Non-Small Cell Lung Cancer via Elevation of ROS Mediated by the EGFR/PI3K/Akt/mTOR Pathway

Non-small cell lung cancer (NSCLC) is one of the most common malignancies in the world. Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) have been used as a first-line treatment for patients harboring with EGFR mutations in advanced NSCLC. Nevertheless, the drug resistance aft...

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Detalles Bibliográficos
Autores principales:	Yan, Shike, Zhang, Bing, Feng, Jingwen, Wu, Haigang, Duan, Namin, Zhu, Yamin, Zhao, Yueliang, Shen, Shuang, Zhang, Kai, Wu, Wenhui, Liu, Ning
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807551/ https://www.ncbi.nlm.nih.gov/pubmed/35126111 http://dx.doi.org/10.3389/fphar.2021.764699

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