The zebrafish embryo as an in vivo model for screening nanoparticle-formulated lipophilic anti-tuberculosis compounds

With the increasing emergence of drug-resistant Mycobacterium tuberculosis strains, new and effective antibiotics against tuberculosis (TB) are urgently needed. However, the high frequency of poorly water-soluble compounds among hits in high-throughput drug screening campaigns is a major obstacle in...

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Detalles Bibliográficos
Autores principales: Knudsen Dal, Nils-Jørgen, Speth, Martin, Johann, Kerstin, Barz, Matthias, Beauvineau, Claire, Wohlmann, Jens, Fenaroli, Federico, Gicquel, Brigitte, Griffiths, Gareth, Alonso-Rodriguez, Noelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807572/
https://www.ncbi.nlm.nih.gov/pubmed/34842273
http://dx.doi.org/10.1242/dmm.049147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807572/
https://www.ncbi.nlm.nih.gov/pubmed/34842273
http://dx.doi.org/10.1242/dmm.049147

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