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Donor-But Not Recipient-Derived Cells Produce Collagen-1 in Chronically Rejected Cardiac Allografts
Fibrosis is a prominent feature of chronic allograft rejection, caused by an excessive production of matrix proteins, including collagen-1. Several cell types produce collagen-1, including mesenchymal fibroblasts and cells of hematopoietic origin. Here, we sought to determine whether tissue-resident...
Autores principales: | Balam, Saidou, Buchtler, Simone, Winter, Frederike, Schmidbauer, Kathrin, Neumayer, Sophia, Talke, Yvonne, Renner, Kerstin, Geissler, Edward K., Mack, Matthias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807636/ https://www.ncbi.nlm.nih.gov/pubmed/35126373 http://dx.doi.org/10.3389/fimmu.2021.816509 |
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