Screening and Identification of the First Non-CRISPR/Cas9-Treated Chinese Miniature Pig With Defective Porcine Endogenous Retrovirus pol Genes

Pig to human xenotransplantation is considered to be a possible approach to alleviate the shortage of human allografts. Porcine endogenous retrovirus (PERV) is the most significant pathogen in xenotransplantation. We screened for pigs that consistently did not transmit human-tropic replication compe...

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Detalles Bibliográficos
Autores principales: Ma, Yuyuan, Jia, Junting, Fan, Rui, Lu, Ying, Zhao, Xiong, Zhong, Yadi, Yang, Jierong, Ma, Limin, Wang, Yanlin, Lv, Maomin, Yang, Haiyuan, Mou, Lisha, Dai, Yifan, Feng, Shutang, Zhang, Jingang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807647/
https://www.ncbi.nlm.nih.gov/pubmed/35126361
http://dx.doi.org/10.3389/fimmu.2021.797608

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