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Primary Thyroid NUT Carcinoma With High PD-L1 Expression and Novel Massive IGKV Gene Fusions: A Case Report With Treatment Implications and Literature Review

BACKGROUND: Nuclear protein in testis (NUT) carcinoma (NC) is a rare and aggressive undifferentiated carcinoma that typically arises from midline supradiaphragmatic structures. It is uniquely driven by a NUT gene rearrangement on chromosome 15q14. Few thyroid NCs have been reported and there are no...

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Detalles Bibliográficos
Autores principales: Zhou, Juan, Duan, Miao, Jiao, Qiong, Chen, Chunyan, Xing, Aiyan, Su, Peng, Tang, Juan, Zhang, Hui, Liu, Zhiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807656/
https://www.ncbi.nlm.nih.gov/pubmed/35127482
http://dx.doi.org/10.3389/fonc.2021.778296