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Computational System Level Approaches for Discerning Reciprocal Regulation of IL10 and IL12 in Leishmaniasis

IL12 and IL10 are two of the major cytokines which control the fate of Leishmaniasis. This paper presents two models healthy state and diseased state which shows how secretion of IL12 is responsible for parasite elimination and IL10 can jeopardize the parasite elimination and promote its survival. E...

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Detalles Bibliográficos
Autores principales: Khandibharad, Shweta, Singh, Shailza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807686/
https://www.ncbi.nlm.nih.gov/pubmed/35126456
http://dx.doi.org/10.3389/fgene.2021.784664

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