EPHA2 mediates PDGFA activity and functions together with PDGFRA as prognostic marker and therapeutic target in glioblastoma

Platelet-derived growth subunit A (PDGFA) plays critical roles in development of glioblastoma (GBM) with substantial evidence from TCGA database analyses and in vivo mouse models. So far, only platelet-derived growth receptor α (PDGFRA) has been identified as receptor for PDGFA. However, PDGFA and P...

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Detalles Bibliográficos
Autores principales: Gai, Qu-Jing, Fu, Zhen, He, Jiang, Mao, Min, Yao, Xiao-Xue, Qin, Yan, Lan, Xi, Zhang, Lin, Miao, Jing-Ya, Wang, Yan-Xia, Zhu, Jiang, Yang, Fei-Cheng, Lu, Hui-Min, Yan, Ze-Xuan, Chen, Fang-Lin, Shi, Yu, Ping, Yi-Fang, Cui, You-Hong, Zhang, Xia, Liu, Xindong, Yao, Xiao-Hong, Lv, Sheng-Qing, Bian, Xiu-Wu, Wang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807725/
https://www.ncbi.nlm.nih.gov/pubmed/35105853
http://dx.doi.org/10.1038/s41392-021-00855-2

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