Cargando…

The DNA methylome of cervical cells can predict the presence of ovarian cancer

The vast majority of epithelial ovarian cancer arises from tissues that are embryologically derived from the Müllerian Duct. Here, we demonstrate that a DNA methylation signature in easy-to-access Müllerian Duct-derived cervical cells from women with and without ovarian cancer (i.e. referred to as t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Barrett, James E., Jones, Allison, Evans, Iona, Reisel, Daniel, Herzog, Chiara, Chindera, Kantaraja, Kristiansen, Mark, Leavy, Olivia C., Manchanda, Ranjit, Bjørge, Line, Zikan, Michal, Cibula, David, Widschwendter, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807742/ https://www.ncbi.nlm.nih.gov/pubmed/35105887 http://dx.doi.org/10.1038/s41467-021-26615-y

Ejemplares similares

DNA methylation signatures to predict the cervicovaginal microbiome status
por: Nené, Nuno R., et al.
Publicado: (2020)

The WID-BC-index identifies women with primary poor prognostic breast cancer based on DNA methylation in cervical samples
por: Barrett, James E., et al.
Publicado: (2022)

Susceptibility to hormone-mediated cancer is reflected by different tick rates of the epithelial and general epigenetic clock
por: Barrett, James E., et al.
Publicado: (2022)

The potential of circulating tumor DNA methylation analysis for the early detection and management of ovarian cancer
por: Widschwendter, Martin, et al.
Publicado: (2017)

Epigenetic reprogramming of fallopian tube fimbriae in BRCA mutation carriers defines early ovarian cancer evolution
por: Bartlett, Thomas E., et al.
Publicado: (2016)

Author Correction: Susceptibility to hormone-mediated cancer is reflected by different tick rates of the epithelial and general epigenetic clock
por: Barrett, J. James E., et al.
Publicado: (2022)

DNA methylation at quantitative trait loci (mQTLs) varies with cell type and nonheritable factors and may improve breast cancer risk assessment
por: Herzog, Chiara, et al.
Publicado: (2023)

The WID‐qEC test: Performance in a hospital‐based cohort and feasibility to detect endometrial and cervical cancers
por: Schreiberhuber, Lena, et al.
Publicado: (2022)

DNA methylation-based detection and prediction of cervical intraepithelial neoplasia grade 3 and invasive cervical cancer with the WID™-qCIN test
por: Herzog, Chiara, et al.
Publicado: (2022)

Methylation patterns in serum DNA for early identification of disseminated breast cancer
por: Widschwendter, Martin, et al.
Publicado: (2017)

A Simple Cervicovaginal Epigenetic Test for Screening and Rapid Triage of Women With Suspected Endometrial Cancer: Validation in Several Cohort and Case/Control Sets
por: Herzog, Chiara, et al.
Publicado: (2022)

The WID-CIN test identifies women with, and at risk of, cervical intraepithelial neoplasia grade 3 and invasive cervical cancer
por: Barrett, James E., et al.
Publicado: (2022)

HOTAIR and its surrogate DNA methylation signature indicate carboplatin resistance in ovarian cancer
por: Teschendorff, Andrew E., et al.
Publicado: (2015)

A BRCA1-mutation associated DNA methylation signature in blood cells predicts sporadic breast cancer incidence and survival
por: Anjum, Shahzia, et al.
Publicado: (2014)

Correction: The Dynamics and Prognostic Potential of DNA Methylation Changes at Stem Cell Gene Loci in Women's Cancer
por: Zhuang, Joanna, et al.
Publicado: (2012)

The Dynamics and Prognostic Potential of DNA Methylation Changes at Stem Cell Gene Loci in Women's Cancer
por: Zhuang, Joanna, et al.
Publicado: (2012)

The association among cervical, anal, and oral HPV infections in high-risk and low-risk women
por: Sehnal, Borek, et al.
Publicado: (2019)

Special Issue “Gynaecological Cancers Risk: Breast Cancer, Ovarian Cancer and Endometrial Cancer”
por: Manchanda, Ranjit
Publicado: (2022)

Synchronous endometrioid endometrial and ovarian carcinomas are biologically related: A clinico-pathological and molecular (next generation sequencing) study of 22 cases
por: Hájková, Nikola, et al.
Publicado: (2019)

A collagen-fibrin patch (Tachosil®) for the prevention of symptomatic lymphoceles after pelvic lymphadenectomy in women with gynecologic malignancies: a randomized clinical trial
por: Grimm, Christoph, et al.
Publicado: (2014)

Methylome analysis of extreme chemoresponsive patients identifies novel markers of platinum sensitivity in high-grade serous ovarian cancer
por: Tomar, Tushar, et al.
Publicado: (2017)

The Diagnostic Accuracy of Ultrasound in Assessment of Myometrial Invasion in Endometrial Cancer: Subjective Assessment versus Objective Techniques
por: Frühauf, Filip, et al.
Publicado: (2017)

Alterations in the methylome of the stromal tumour microenvironment signal the presence and severity of prostate cancer
por: Lawrence, Mitchell G., et al.
Publicado: (2020)

Antiprogestins reduce epigenetic field cancerization in breast tissue of young healthy women
por: Bartlett, Thomas E., et al.
Publicado: (2022)

Correction: Antiprogestins reduce epigenetic field cancerization in breast tissue of young healthy women
por: Bartlett, Thomas E., et al.
Publicado: (2022)

The antimicrobial polymer PHMB enters cells and selectively condenses bacterial chromosomes
por: Chindera, Kantaraja, et al.
Publicado: (2016)

Pathogen- and Host-Directed Antileishmanial Effects Mediated by Polyhexanide (PHMB)
por: Firdessa, Rebuma, et al.
Publicado: (2015)

PARP inhibitors in ovarian cancer
por: Cibula, David, et al.
Publicado: (2015)

Detection of ovarian cancer using plasma cell-free DNA methylomes
por: Lu, Huaiwu, et al.
Publicado: (2022)

Chicken Hypothalamic and Ovarian DNA Methylome Alteration in Response to Forced Molting
por: Zhang, Tongyu, et al.
Publicado: (2023)

The Emerging Role of CD24 in Cancer Theranostics—A Novel Target for Fluorescence Image-Guided Surgery in Ovarian Cancer and Beyond
por: Kleinmanns, Katrin, et al.
Publicado: (2020)

MPC-1 DNA methylome analysis suggested the presence of “true” IDH-wildtype lower-grade gliomas
por: Satomi, Kaishi, et al.
Publicado: (2021)

4D Doppler Ultrasound in High Grade Serous Ovarian Cancer Vascularity Evaluation—Preliminary Study
por: Kudla, Marek Jerzy, et al.
Publicado: (2021)

Comprehensive Analysis of the Transcriptome-Wide m6A Methylome in Endometrioid Ovarian Cancer
por: Yang, Li, et al.
Publicado: (2022)

Impact of FecB Mutation on Ovarian DNA Methylome in Small-Tail Han Sheep
por: Xie, Lingli, et al.
Publicado: (2023)

Exploring the cancer methylome
por: Berman, Benjamin P, et al.
Publicado: (2012)

The methylomes of six bacteria
por: Murray, Iain A., et al.
Publicado: (2014)

The methylomes of six bacteria
por: Murray, Iain A., et al.
Publicado: (2012)

Prodigious plant methylomes
por: Gehring, Mary
Publicado: (2016)

Methylome evolution in plants
por: Vidalis, Amaryllis, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_bbcdh1ddbifo9rvdp1b55r6908