SARS-CoV-2 genomes from Saudi Arabia implicate nucleocapsid mutations in host response and increased viral load

Monitoring SARS-CoV-2 spread and evolution through genome sequencing is essential in handling the COVID-19 pandemic. Here, we sequenced 892 SARS-CoV-2 genomes collected from patients in Saudi Arabia from March to August 2020. We show that two consecutive mutations (R203K/G204R) in the nucleocapsid (...

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Detalles Bibliográficos
Autores principales: Mourier, Tobias, Shuaib, Muhammad, Hala, Sharif, Mfarrej, Sara, Alofi, Fadwa, Naeem, Raeece, Alsomali, Afrah, Jorgensen, David, Subudhi, Amit Kumar, Ben Rached, Fathia, Guan, Qingtian, Salunke, Rahul P., Ooi, Amanda, Esau, Luke, Douvropoulou, Olga, Nugmanova, Raushan, Perumal, Sadhasivam, Zhang, Huoming, Rajan, Issaac, Al-Omari, Awad, Salih, Samer, Shamsan, Abbas, Al Mutair, Abbas, Taha, Jumana, Alahmadi, Abdulaziz, Khotani, Nashwa, Alhamss, Abdelrahman, Mahmoud, Ahmed, Alquthami, Khaled, Dageeg, Abdullah, Khogeer, Asim, Hashem, Anwar M., Moraga, Paula, Volz, Eric, Almontashiri, Naif, Pain, Arnab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807822/
https://www.ncbi.nlm.nih.gov/pubmed/35105893
http://dx.doi.org/10.1038/s41467-022-28287-8

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