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Cis-regulatory hubs: a new 3D model of complex disease genetics with an application to schizophrenia
The 3D conformation of the chromatin creates complex networks of noncoding regulatory regions (distal elements) and promoters impacting gene regulation. Despite the importance of the role of noncoding regions in complex diseases, little is known about their interplay within regulatory hubs and impli...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Life Science Alliance LLC
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807870/ https://www.ncbi.nlm.nih.gov/pubmed/35086934 http://dx.doi.org/10.26508/lsa.202101156 |