Age-related differences in immune dynamics during SARS-CoV-2 infection in rhesus macaques

Advanced age is a key predictor of severe COVID-19. To gain insight into this relationship, we used the rhesus macaque model of SARS-CoV-2 infection. Eight older and eight younger macaques were inoculated with SARS-CoV-2. Animals were evaluated using viral RNA quantification, clinical observations,...

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Detalles Bibliográficos
Autores principales: Speranza, Emily, Purushotham, Jyothi N, Port, Julia R, Schwarz, Benjamin, Flagg, Meaghan, Williamson, Brandi N, Feldmann, Friederike, Singh, Manmeet, Pérez-Pérez, Lizzette, Sturdevant, Gail L, Roberts, Lydia M, Carmody, Aaron, Schulz, Jonathan E, van Doremalen, Neeltje, Okumura, Atsushi, Lovaglio, Jamie, Hanley, Patrick W, Shaia, Carl, Germain, Ronald N, Best, Sonja M, Munster, Vincent J, Bosio, Catharine M, de Wit, Emmie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807873/
https://www.ncbi.nlm.nih.gov/pubmed/35039442
http://dx.doi.org/10.26508/lsa.202101314

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