Epigenetic modifier balances Mapk and Wnt signalling in differentiation of goblet and Paneth cells

Differentiation and lineage specification are controlled by cooperation of growth factor signalling. The involvement of epigenetic regulators in lineage specification remains largely elusive. Here, we show that the histone methyltransferase Mll1 prevents intestinal progenitor cells from differentiat...

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Detalles Bibliográficos
Autores principales: Grinat, Johanna, Kosel, Frauke, Goveas, Neha, Kranz, Andrea, Alexopoulou, Dimitra, Rajewsky, Klaus, Sigal, Michael, Stewart, A Francis, Heuberger, Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807877/
https://www.ncbi.nlm.nih.gov/pubmed/35064075
http://dx.doi.org/10.26508/lsa.202101187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807877/
https://www.ncbi.nlm.nih.gov/pubmed/35064075
http://dx.doi.org/10.26508/lsa.202101187

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