Cargando…
Epigenetic modifier balances Mapk and Wnt signalling in differentiation of goblet and Paneth cells
Differentiation and lineage specification are controlled by cooperation of growth factor signalling. The involvement of epigenetic regulators in lineage specification remains largely elusive. Here, we show that the histone methyltransferase Mll1 prevents intestinal progenitor cells from differentiat...
Autores principales: | Grinat, Johanna, Kosel, Frauke, Goveas, Neha, Kranz, Andrea, Alexopoulou, Dimitra, Rajewsky, Klaus, Sigal, Michael, Stewart, A Francis, Heuberger, Julian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807877/ https://www.ncbi.nlm.nih.gov/pubmed/35064075 http://dx.doi.org/10.26508/lsa.202101187 |
Ejemplares similares
-
The epigenetic regulator Mll1 is required for Wnt-driven intestinal tumorigenesis and cancer stemness
por: Grinat, Johanna, et al.
Publicado: (2020) -
NF-κB determines Paneth versus goblet cell fate decision in the small intestine
por: Brischetto, Cristina, et al.
Publicado: (2021) -
PANETH AND GOBLET CELL RENEWAL IN MOUSE DUODENAL CRYPTS
por: Troughton, W. David, et al.
Publicado: (1969) -
MLL1 is required for maintenance of intestinal stem cells
por: Goveas, Neha, et al.
Publicado: (2021) -
Lkb1 Deficiency Alters Goblet and Paneth Cell Differentiation in the Small Intestine
por: Shorning, Boris Y., et al.
Publicado: (2009)