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MYD88(L265P) and CD79B double mutations type (MCD type) of diffuse large B-cell lymphoma: mechanism, clinical characteristics, and targeted therapy

MYD88/CD79B-mutated (MCD) genotype is a genetic subgroup of diffuse large B-cell lymphoma (DLBCL) with the co-occurrence of MYD88(L265P) and CD79B mutations. MCD genotype is characterized by poor prognosis and extranodal involvement especially in immune-privileged sites. MCD model is dominated by ac...

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Detalles Bibliográficos
Autores principales: Chen, Rongrong, Zhou, De, Wang, Lulu, Zhu, Lixia, Ye, Xiujin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8808040/
https://www.ncbi.nlm.nih.gov/pubmed/35126963
http://dx.doi.org/10.1177/20406207211072839