Cargando…

Targeting AraC-Resistant Acute Myeloid Leukemia by Dual Inhibition of CDK9 and Bcl-2: A Systematic Review and Meta-Analysis

PURPOSE: This study aims to determine the influence of targeting araC-resistant acute myeloid leukemia by dual inhibition cyclin-dependent protein kinase (CDK9) and B-cell lymphoma-2 （Bcl-2). METHOD: The c-Myc inhibitor 10058-F4 and the CDK9 inhibitor AZD4573 were used to determine the cell cycle ar...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Linzhang, Han, Chengwu, Yu, Xueying, Shen, Jun, Cao, Yongtong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8808115/ https://www.ncbi.nlm.nih.gov/pubmed/35126914 http://dx.doi.org/10.1155/2022/2842066

Ejemplares similares

Retracted: Targeting AraC-Resistant Acute Myeloid Leukemia by Dual Inhibition of CDK9 and Bcl-2: A Systematic Review and Meta-Analysis
por: Healthcare Engineering, Journal of
Publicado: (2023)

DNA tape measurements of AraC
por: Rodgers, Michael E., et al.
Publicado: (2008)

AraC-Based Biosensor for the Detection of Isoprene in E. coli
por: Bhat, Shrilaxmi, et al.
Publicado: (2023)

Liposomally trapped AraCTP to overcome AraC resistance in a murine lymphoma in vitro.
por: Richardson, V. J., et al.
Publicado: (1982)

Blockade of CD82 by a monoclonal antibody potentiates anti-leukemia effects of AraC in vivo
por: Nishioka, Chie, et al.
Publicado: (2015)

Characterisation of a putative AraC transcriptional regulator from Mycobacterium smegmatis
por: Evangelopoulos, Dimitrios, et al.
Publicado: (2014)

FoxR is an AraC‐like transcriptional regulator of ferrioxamine uptake in Salmonella enterica
por: Saldaña‐Ahuactzi, Zeus, et al.
Publicado: (2022)

A large family of anti‐activators accompanying XylS/AraC family regulatory proteins
por: Santiago, Araceli E., et al.
Publicado: (2016)

A new class of inhibitors of the AraC family virulence regulator Vibrio cholerae ToxT
por: Woodbrey, Anne K., et al.
Publicado: (2017)

The AraC Negative Regulator family modulates the activity of histone-like proteins in pathogenic bacteria
por: Santiago, Araceli E., et al.
Publicado: (2017)

Structural basis of transcription activation by Rob, a pleiotropic AraC/XylS family regulator
por: Shi, Jing, et al.
Publicado: (2022)

Signal amplification of araC pBAD using a standardized translation initiation region
por: Shilling, Patrick J, et al.
Publicado: (2022)

Low dose docosahexaenoic acid protects normal colonic epithelial cells from araC toxicity
por: Cha, Ming C, et al.
Publicado: (2005)

Characterization of a novel AraC/XylS-regulated family of N-acyltransferases in pathogens of the order Enterobacterales
por: Belmont-Monroy, Laura, et al.
Publicado: (2020)

AraC interacts with p75(NTR) transmembrane domain to induce cell death of mature neurons
por: Lopes-Rodrigues, Vanessa, et al.
Publicado: (2023)

Computer-Based Annotation of Putative AraC/XylS-Family Transcription Factors of Known Structure but Unknown Function
por: Schüller, Andreas, et al.
Publicado: (2012)

1.65 Å resolution structure of the AraC-family transcriptional activator ToxT from Vibrio cholerae
por: Li, Jiaqin, et al.
Publicado: (2016)

A mannose-sensing AraC-type transcriptional activator regulates cell–cell aggregation of Vibrio cholerae
por: Lee, Hye-Young, et al.
Publicado: (2022)

The AraC-Type Transcriptional Regulator GliR (PA3027) Activates Genes of Glycerolipid Metabolism in Pseudomonas aeruginosa
por: Kotecka, Karolina, et al.
Publicado: (2021)

Unveiling a Virulence-Regulating Mechanism in Aeromonas hydrophila: a Quantitative Exoproteomic Analysis of an AraC-Like Protein
por: Zhang, Lishan, et al.
Publicado: (2023)

CDK9 inhibitors in acute myeloid leukemia
por: Boffo, Silvia, et al.
Publicado: (2018)

Development of a new fluorescent reporter:operator system: location of AraC regulated genes in Escherichia coli K-12
por: Sellars, Laura E., et al.
Publicado: (2017)

Diffusible Signal Factors Act through AraC-Type Transcriptional Regulators as Chemical Cues To Repress Virulence of Enteric Pathogens
por: Bosire, Erick Maosa, et al.
Publicado: (2020)

Optimization of cytarabine (ARA-C) therapy for acute myeloid leukemia
por: Momparler, Richard L
Publicado: (2013)

An improved Escherichia coli strain to host gene regulatory networks involving both the AraC and LacI inducible transcription factors
por: Kogenaru, Manjunatha, et al.
Publicado: (2014)

SAV742, a Novel AraC-Family Regulator from Streptomyces avermitilis, Controls Avermectin Biosynthesis, Cell Growth and Development
por: Sun, Di, et al.
Publicado: (2016)

OnfD, an AraC-Type Transcriptional Regulator Encoded by Rhizobium tropici CIAT 899 and Involved in Nod Factor Synthesis and Symbiosis
por: del Cerro, Pablo, et al.
Publicado: (2020)

IMiDs mobilize acute myeloid leukemia blasts to peripheral blood through downregulation of CXCR4 but fail to potentiate AraC/Idarubicin activity in preclinical models of non del5q/5q- AML
por: Lopez-Millan, Belen, et al.
Publicado: (2018)

4-Chlorophenol Oxidation Depends on the Activation of an AraC-Type Transcriptional Regulator, CphR, in Rhodococcus sp. Strain YH-5B
por: Zhang, Hui, et al.
Publicado: (2018)

R-CHOP intensification with mid-cycle methotrexate and consolidating AraC/TT with BCNU/aHSCT in primary aggressive lymphoma with CNS involvement
por: Steinhardt, Maximilian J., et al.
Publicado: (2021)

Inhibition of CDK9 by voruciclib synergistically enhances cell death induced by the Bcl-2 selective inhibitor venetoclax in preclinical models of acute myeloid leukemia
por: Luedtke, Daniel A., et al.
Publicado: (2020)

Randomized evaluation of quizartinib and low-dose ara-C vs low-dose ara-C in older acute myeloid leukemia patients
por: Dennis, Mike, et al.
Publicado: (2021)

BfvR, an AraC-Family Regulator, Controls Biofilm Formation and pH6 Antigen Production in Opposite Ways in Yersinia pestis Biovar Microtus
por: Fang, Haihong, et al.
Publicado: (2018)

AraC-induced neuron-like differentiation of human NTERA2/D1 cells and quantification of endogenous pre-mir-106b and 19b levels
por: Kaneko, Yuka, et al.
Publicado: (2023)

Radotinib enhances cytarabine (Ara-C)-induced acute myeloid leukemia cell death
por: Heo, Sook-Kyoung, et al.
Publicado: (2020)

Torres Vargas, Georgina Araceli, Biblioteca digital
por: GARDUÑO V., ROBERTO
Publicado: (2005)

Structures of the Escherichia coli transcription activator and regulator of diauxie, XylR: an AraC DNA-binding family member with a LacI/GalR ligand-binding domain
por: Ni, Lisheng, et al.
Publicado: (2013)

Adjusting the neuron to astrocyte ratio with cytostatics in hippocampal cell cultures from postnatal rats: A comparison of cytarabino furanoside (AraC) and 5-fluoro-2’-deoxyuridine (FUdR)
por: Lesslich, Heiko M., et al.
Publicado: (2022)

Targeting Bcl-2 Proteins in Acute Myeloid Leukemia
por: Wei, Yunxiong, et al.
Publicado: (2020)

Ara-C, Idarubicine and Gentuzumab Ozogamicin (AIM) as Salvage Treatment in Advanced Acute Myeloid Leukemia Patients
por: Capria, Saveria, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_gt8sjksi386cqtotejtqov07dc