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Effect and Safety Analysis of PRP and Yifu Combined with Ultrapulsed CO(2) Lattice Laser in Patients with Sunken Acne Scar

OBJECTIVE: To investigate the effect and safety of PRP and Yifu combined with ultrapulsed CO(2) lattice laser in patients with sunken acne scar. METHODS: 700 subjects were selected from the group of patients with sunken acne scar treated in our hospital from November 2010 to December 2020. They were...

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Autores principales: Wang, Yuyan, Yu, Wei, Zhang, Jufang, Li, Jinsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8808142/
https://www.ncbi.nlm.nih.gov/pubmed/35126939
http://dx.doi.org/10.1155/2022/6803988
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author Wang, Yuyan
Yu, Wei
Zhang, Jufang
Li, Jinsheng
author_facet Wang, Yuyan
Yu, Wei
Zhang, Jufang
Li, Jinsheng
author_sort Wang, Yuyan
collection PubMed
description OBJECTIVE: To investigate the effect and safety of PRP and Yifu combined with ultrapulsed CO(2) lattice laser in patients with sunken acne scar. METHODS: 700 subjects were selected from the group of patients with sunken acne scar treated in our hospital from November 2010 to December 2020. They were divided into control group (n = 350) and study group (n = 350). The grouping was mainly based on the random number table method. Patients in the control group were treated with ultrapulse CO(2) lattice laser, while those in the study group were treated with ultrapulse CO(2) lattice laser combined with PRP and Yifu. The clinical effect, scar improvement and quality of life before and after treatment, and adverse events during treatment were compared between the two groups. The clinical effect was categorized into cure after treatment, significant effect, effective, and ineffective. The total effective rate = 1 − ineffective rate. RESULTS: After treatment, the total effective rate of the study group (81.43%) was higher than that of the control group (70.00%). After treatment, ECCA, VSS scores, daily activities, symptoms and feelings, work and study, leisure and entertainment, interpersonal relationship, treatment status, and total scores were all lower in both groups than before treatment, and the study group was lower than the control group. During the treatment, the incidence of adverse events in the study group (17.33%) was lower than that in the control group (28.57%), P < 0.05. CONCLUSION: PRP and Yifu combined with ultrapulse CO(2) lattice laser in the treatment of sunken acne scar can effectively improve the scar, reduce the incidence of adverse events, and the treatment effect is obvious, which can improve the quality of life of the patients.
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spelling pubmed-88081422022-02-03 Effect and Safety Analysis of PRP and Yifu Combined with Ultrapulsed CO(2) Lattice Laser in Patients with Sunken Acne Scar Wang, Yuyan Yu, Wei Zhang, Jufang Li, Jinsheng J Healthc Eng Research Article OBJECTIVE: To investigate the effect and safety of PRP and Yifu combined with ultrapulsed CO(2) lattice laser in patients with sunken acne scar. METHODS: 700 subjects were selected from the group of patients with sunken acne scar treated in our hospital from November 2010 to December 2020. They were divided into control group (n = 350) and study group (n = 350). The grouping was mainly based on the random number table method. Patients in the control group were treated with ultrapulse CO(2) lattice laser, while those in the study group were treated with ultrapulse CO(2) lattice laser combined with PRP and Yifu. The clinical effect, scar improvement and quality of life before and after treatment, and adverse events during treatment were compared between the two groups. The clinical effect was categorized into cure after treatment, significant effect, effective, and ineffective. The total effective rate = 1 − ineffective rate. RESULTS: After treatment, the total effective rate of the study group (81.43%) was higher than that of the control group (70.00%). After treatment, ECCA, VSS scores, daily activities, symptoms and feelings, work and study, leisure and entertainment, interpersonal relationship, treatment status, and total scores were all lower in both groups than before treatment, and the study group was lower than the control group. During the treatment, the incidence of adverse events in the study group (17.33%) was lower than that in the control group (28.57%), P < 0.05. CONCLUSION: PRP and Yifu combined with ultrapulse CO(2) lattice laser in the treatment of sunken acne scar can effectively improve the scar, reduce the incidence of adverse events, and the treatment effect is obvious, which can improve the quality of life of the patients. Hindawi 2022-01-25 /pmc/articles/PMC8808142/ /pubmed/35126939 http://dx.doi.org/10.1155/2022/6803988 Text en Copyright © 2022 Yuyan Wang et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Wang, Yuyan
Yu, Wei
Zhang, Jufang
Li, Jinsheng
Effect and Safety Analysis of PRP and Yifu Combined with Ultrapulsed CO(2) Lattice Laser in Patients with Sunken Acne Scar
title Effect and Safety Analysis of PRP and Yifu Combined with Ultrapulsed CO(2) Lattice Laser in Patients with Sunken Acne Scar
title_full Effect and Safety Analysis of PRP and Yifu Combined with Ultrapulsed CO(2) Lattice Laser in Patients with Sunken Acne Scar
title_fullStr Effect and Safety Analysis of PRP and Yifu Combined with Ultrapulsed CO(2) Lattice Laser in Patients with Sunken Acne Scar
title_full_unstemmed Effect and Safety Analysis of PRP and Yifu Combined with Ultrapulsed CO(2) Lattice Laser in Patients with Sunken Acne Scar
title_short Effect and Safety Analysis of PRP and Yifu Combined with Ultrapulsed CO(2) Lattice Laser in Patients with Sunken Acne Scar
title_sort effect and safety analysis of prp and yifu combined with ultrapulsed co(2) lattice laser in patients with sunken acne scar
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8808142/
https://www.ncbi.nlm.nih.gov/pubmed/35126939
http://dx.doi.org/10.1155/2022/6803988
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