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Degradation of the E. coli antitoxin MqsA by the proteolytic complex ClpXP is regulated by zinc occupancy and oxidation

It is well established that the antitoxins of toxin–antitoxin (TA) systems are selectively degraded by bacterial proteases in response to stress. However, how distinct stressors result in the selective degradation of specific antitoxins remain unanswered. MqsRA is a TA system activated by various st...

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Detalles Bibliográficos
Autores principales: Vos, Margaret R., Piraino, Benjamin, LaBreck, Christopher J., Rahmani, Negar, Trebino, Catherine E., Schoenle, Marta, Peti, Wolfgang, Camberg, Jodi L., Page, Rebecca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8808172/
https://www.ncbi.nlm.nih.gov/pubmed/34974059
http://dx.doi.org/10.1016/j.jbc.2021.101557

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