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Temporal Analysis of Protein Ubiquitylation and Phosphorylation During Parkin-Dependent Mitophagy

Mitophagy, the selective degradation of mitochondria by autophagy, affects defective mitochondria following damage or stress. At the onset of mitophagy, parkin ubiquitylates proteins on the mitochondrial outer membrane. While the role of parkin at the onset of mitophagy is well understood, less is k...

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Detalles Bibliográficos
Autores principales: Zittlau, Katharina I., Lechado-Terradas, Anna, Nalpas, Nicolas, Geisler, Sven, Kahle, Philipp J., Macek, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8808264/
https://www.ncbi.nlm.nih.gov/pubmed/34974192
http://dx.doi.org/10.1016/j.mcpro.2021.100191

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