Cargando…

New genetic variants of TET2 and ASXL1 identified by next generation sequencing and pyrosequencing in a patient with MDS-RS-MLD and secondary acute myeloid leukemia

Myelodysplastic syndromes (MDS) are a heterogeneous group of myeloid neoplasms characterized by the presence of cytopenias, ineffective hematopoiesis and frequent transformation into secondary acute myeloid leukemia (secAML). Recent genomic studies provide unprecedented insight into the molecular la...

Descripción completa

Detalles Bibliográficos
Autores principales:	Adamska, Monika Małgorzata, Kowal-Wiśniewska, Ewelina, Kiwerska, Katarzyna, Ustaszewski, Adam, Czerwińska-Rybak, Joanna, Kanduła, Zuzanna, Wojtaszewska, Marzena, Barańska, Marta, Pruchniewski, Łukasz, Lewandowski, Krzysztof, Jarmuż-Szymczak, Małgorzata, Gil, Lidia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Termedia Publishing House 2021
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8808311/ https://www.ncbi.nlm.nih.gov/pubmed/35125953 http://dx.doi.org/10.5114/ceji.2021.111166

Ejemplares similares

Global DNA Methylation Profiling Reveals Differentially Methylated CpGs between Salivary Gland Pleomorphic Adenomas with Distinct Clinical Course
por: Kiwerska, Katarzyna, et al.
Publicado: (2022)

Alteration of the Early Development Environment by Maternal Diet and the Occurrence of Autistic-like Phenotypes in Rat Offspring
por: Gawlińska, Kinga, et al.
Publicado: (2021)

Prognostic significance of the methylation of Wnt pathway antagonists—CXXC4, DACT2, and the inhibitors of sonic hedgehog signaling—ZIC1, ZIC4, and HHIP in head and neck squamous cell carcinomas
por: Paluszczak, Jarosław, et al.
Publicado: (2016)

Loss of the MAF Transcription Factor in Laryngeal Squamous Cell Carcinoma
por: Janiszewska, Joanna, et al.
Publicado: (2021)

Induction of expression of aryl hydrocarbon receptor-dependent genes in human HepaRG cell line modified by shRNA and treated with β-naphthoflavone
por: Brauze, Damian, et al.
Publicado: (2016)

Assessing Various Control Samples for Microarray Gene Expression Profiling of Laryngeal Squamous Cell Carcinoma
por: Ustaszewski, Adam, et al.
Publicado: (2021)

Infrequent occurrence of TET1, TET3, and ASXL2 mutations in myelodysplastic/myeloproliferative neoplasms
por: Lasho, Terra L., et al.
Publicado: (2018)

SETBP1 Mutations Drive Leukemic Transformation in ASXL1-Mutated MDS
por: Inoue, Daichi, et al.
Publicado: (2014)

A treatment-refractory aggressive MDS-MLD with multiple highly complex chromosome 5 intrachromosomal rearrangements: a case report
por: Sasi, Ramakrishnan, et al.
Publicado: (2022)

TET2 deficiency promotes MDS-associated leukemogenesis
por: Huang, Feiteng, et al.
Publicado: (2022)

ASXL1 frameshift mutations drive inferior outcomes in CMML without negative impact in MDS
por: Sallman, David A, et al.
Publicado: (2017)

The negative regulators of Wnt pathway—DACH1, DKK1, and WIF1 are methylated in oral and oropharyngeal cancer and WIF1 methylation predicts shorter survival
por: Paluszczak, Jarosław, et al.
Publicado: (2014)

Prognostic interaction between ASXL1 and TET2 mutations in chronic myelomonocytic leukemia
por: Patnaik, M M, et al.
Publicado: (2016)

ASXL1 mutations with serum EPO levels predict poor response to darbepoetin alfa in lower-risk MDS: W-JHS MDS01 trial
por: Morita, Yasuyoshi, et al.
Publicado: (2022)

Small RNA-Seq Reveals Similar miRNA Transcriptome in Children and Young Adults with T-ALL and Indicates miR-143-3p as Novel Candidate Tumor Suppressor in This Leukemia
por: Dawidowska, Małgorzata, et al.
Publicado: (2022)

Correction: TET2 deficiency promotes MDS-associated leukemogenesis
por: Huang, Feiteng, et al.
Publicado: (2023)

Combined deletion and DNA methylation result in silencing of FAM107A gene in laryngeal tumors
por: Kiwerska, Katarzyna, et al.
Publicado: (2017)

BCR::ABL1-like acute lymphoblastic leukaemia: a single institution experience on identification of potentially therapeutic targetable cases
por: Płotka, Anna, et al.
Publicado: (2023)

Single nucleotide polymorphism rs11614913 associated with CC genotype in miR-196a2 is overrepresented in laryngeal squamous cell carcinoma, but not salivary gland tumors in Polish population
por: Skalski, Marcin, et al.
Publicado: (2018)

Infantile Metachromatic Leukodystrophy (MLD): A Rare Case
por: Gajbhiye, Varsha, et al.
Publicado: (2022)

Copy number gains of the putative CRKL oncogene in laryngeal squamous cell carcinoma result in strong nuclear expression of the protein and influence cell proliferation and migration
por: Kostrzewska-Poczekaj, Magdalena, et al.
Publicado: (2020)

Rapid progression of myelofibrosis in polycythemia vera patient carrying SRSF2 c.284C>A p.(Pro95His) and unique ASXL1 splice site c.1720‐2A>G variant
por: Kanduła, Zuzanna, et al.
Publicado: (2022)

P857: BORTEZOMIB- AND CARFILZOMIB-RESISTANT MYELOMA CELLS SHOW INCREASED ACTIVITY OF ALL THREE ARMS OF UNFOLDED PROTEIN RESPONSE AND ENRICHMENT OF SIRTUIN SIGNALING PATHWAY
por: Kubicki, T., et al.
Publicado: (2022)

Brain MRI and biological diagnosis in five Tunisians MLD patients
por: Barboura, Ilhem, et al.
Publicado: (2012)

Phosphorus monolayer doping (MLD) of silicon on insulator (SOI) substrates
por: Kennedy, Noel, et al.
Publicado: (2018)

B-Cell Chronic Lymphocytic Leukemia with 11q22.3 Rearrangement in Patient with Chronic Myeloid Leukemia Treated with Imatinib
por: Lewandowski, Krzysztof, et al.
Publicado: (2016)

HDAC4 inhibition disrupts TET2 function in high-risk MDS and AML
por: Huang, Feiteng, et al.
Publicado: (2020)

Impact of TET2, SRSF2, ASXL1 and SETBP1 mutations on survival of patients with chronic myelomonocytic leukemia
por: Cui, Yajuan, et al.
Publicado: (2015)

P1001: DNMT3A/TET2/ASXL1 MUTATIONS DETERMINE THROMBOTIC RISK IN POLYCYTHAEMIA VERA
por: Segura Diaz, A., et al.
Publicado: (2022)

Narrowing the localization of the region breakpoint in most frequent Robertsonian translocations
por: Jarmuz-Szymczak, Malgorzata, et al.
Publicado: (2014)

TET2, ASXL1, IDH1, and IDH2 Single Nucleotide Polymorphisms in Turkish Patients with Chronic Myeloproliferative Neoplasms
por: Soyer, Nur, et al.
Publicado: (2017)

Thrombotic Risk Detection in Patients with Polycythemia Vera: The Predictive Role of DNMT3A/TET2/ASXL1 Mutations
por: Segura-Díaz, Adrián, et al.
Publicado: (2020)

The Effect of Lysozyme on the Production of Tetanus Toxin. II. Mouse M.L.D.
por: Stone, Joseph L.
Publicado: (1953)

Electrochemically Active In Situ Crystalline Lithium-Organic Thin Films by ALD/MLD
por: Multia, Jenna, et al.
Publicado: (2020)

MLD: An Intelligent Memory Leak Detection Scheme Based on Defect Modes in Software
por: Yuan, Ling, et al.
Publicado: (2022)

Single Nucleotide Polymorphism Array Lesions, TET2, DNMT3A, ASXL1 and CBL Mutations Are Present in Systemic Mastocytosis
por: Traina, Fabiola, et al.
Publicado: (2012)

Staphylococcus aureus from Atopic Dermatitis Patients: Its Genetic Structure and Susceptibility to Phototreatment
por: Ogonowska, Patrycja, et al.
Publicado: (2023)

Off-Label Use of Botulinum Toxin in Dermatology—Current State of the Art
por: Lewandowski, Miłosz, et al.
Publicado: (2022)

Could a handbook serve as a useful educational intervention in improving disease knowledge? A cross-sectional study among patients with hidradenitis suppurativa in Poland
por: Lewandowski, Miłosz, et al.
Publicado: (2022)

Rapid and Durable Complete Remission of Refractory AITL with Azacitidine Treatment in Absence of TET2 Mutation or Concurrent MDS
por: Gregory, Gareth P., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_5lb9956b4001ro680s2laqafj6