Exosomes derived from γδ-T cells synergize with radiotherapy and preserve antitumor activities against nasopharyngeal carcinoma in immunosuppressive microenvironment

BACKGROUND: Radiotherapy is the first-line treatment for patients nasopharyngeal carcinoma (NPC), but its therapeutic efficacy is poor in some patients due to radioresistance. Adoptive T cell-based immunotherapy has also shown promise to control NPC; however, its antitumor efficacy may be attenuated...

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Detalles Bibliográficos
Autores principales: Wang, Xiwei, Zhang, Yanmei, Mu, Xiaofeng, Tu, Chloe Ran, Chung, Yuet, Tsao, Sai Wah, Chan, Godfrey Chi-Fung, Leung, Wing-Hang, Lau, Yu-lung, Liu, Yinping, Tu, Wenwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Clinical/Translational Cancer Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8808451/
https://www.ncbi.nlm.nih.gov/pubmed/35105688
http://dx.doi.org/10.1136/jitc-2021-003832

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