Elevated proportion of TLR2- and TLR4-expressing Th17-like cells and activated memory B cells was associated with clinical activity of cerebral cavernous malformations

BACKGROUND: Recent evidences have suggested the involvement of toll-like receptor (TLR)-4 in the pathogenesis of cerebral cavernous malformations (CCM). Elevated frequency of TLR(+)T-cells has been associated with neurological inflammatory disorders. As T-cells and B-cells are found in CCM lesions,...

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Detalles Bibliográficos
Autores principales: Castro, Camilla, Oyamada, Hugo A. A., Cafasso, Marcos Octávio S. D., Lopes, Lana M., Monteiro, Clarice, Sacramento, Priscila M., Alves-Leon, Soniza Vieira, da Fontoura Galvão, Gustavo, Hygino, Joana, de Souza, Jorge Paes Barreto Marcondes, Bento, Cleonice A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8808981/
https://www.ncbi.nlm.nih.gov/pubmed/35109870
http://dx.doi.org/10.1186/s12974-022-02385-2

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