CpG site hypomethylation at ETS1-binding region regulates DLK1 expression in Chinese patients with Tetralogy of Fallot

Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart malformation accounting for ~10% of cases. Although the pathogenesis of TOF is complex and largely unknown, epigenetics plays a huge role, specifically DNA methylation. The protein δ like non-canonical Notch ligand 1 (DLK1) gene...

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Detalles Bibliográficos
Autores principales: Tian, Guixiang, He, Lili, Gu, Ruoyi, Sun, Jingwei, Chen, Weicheng, Qian, Yanyan, Ma, Xiaojing, Yan, Weili, Zhao, Zhenshan, Xu, Ziqing, Suo, Meijiao, Sheng, Wei, Huang, Guoying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809049/
https://www.ncbi.nlm.nih.gov/pubmed/35059744
http://dx.doi.org/10.3892/mmr.2022.12609

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