Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2

There is an urgent need for antiviral agents that treat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We screened a library of 1900 clinically safe drugs against OC43, a human beta coronavirus that causes the common cold, and evaluated the top hits against SARS-CoV-2. Twent...

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Бібліографічні деталі
Автори: Drayman, Nir, DeMarco, Jennifer K., Jones, Krysten A., Azizi, Saara-Anne, Froggatt, Heather M., Tan, Kemin, Maltseva, Natalia Ivanovna, Chen, Siquan, Nicolaescu, Vlad, Dvorkin, Steve, Furlong, Kevin, Kathayat, Rahul S., Firpo, Mason R., Mastrodomenico, Vincent, Bruce, Emily A., Schmidt, Madaline M., Jedrzejczak, Robert, Muñoz-Alía, Miguel Á., Schuster, Brooke, Nair, Vishnu, Han, Kyu-yeon, O’Brien, Amornrat, Tomatsidou, Anastasia, Meyer, Bjoern, Vignuzzi, Marco, Missiakas, Dominique, Botten, Jason W., Brooke, Christopher B., Lee, Hyun, Baker, Susan C., Mounce, Bryan C., Heaton, Nicholas S., Severson, William E., Palmer, Kenneth E., Dickinson, Bryan C., Joachimiak, Andrzej, Randall, Glenn, Tay, Savaş
Формат: Online Стаття Текст
Мова:English
Опубліковано: American Association for the Advancement of Science 2021
Предмети:
Reports
Онлайн доступ:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809056/
https://www.ncbi.nlm.nih.gov/pubmed/34285133
http://dx.doi.org/10.1126/science.abg5827

Інтернет

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809056/
https://www.ncbi.nlm.nih.gov/pubmed/34285133
http://dx.doi.org/10.1126/science.abg5827

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