A COVID-19 family cluster with retinitis pigmentosa and hypogammaglobulinemia

Hypogammaglobulinemia is a heterogeneous group of innate and acquired antibody deficiency with variable disease severity, recurrent pneumonia, and bronchiectasis. The outcome of COVID in patients with hypogammaglobulinemia is variable depending on age, comorbidities, type of immunodeficiency, and us...

Descripción completa

Detalles Bibliográficos
Autores principales: Alshukairi, Abeer N., Aldabbagh, Yasser A., Sayes, Najla M., Al Gethamy, Manal M., Alghamdi, Mohammed G., Rahbeeni, Zuhair A., Dada, Ashraf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809126/
https://www.ncbi.nlm.nih.gov/pubmed/35198051
http://dx.doi.org/10.4103/atm.atm_520_21
_version_ 1784643954299371520
author Alshukairi, Abeer N.
Aldabbagh, Yasser A.
Sayes, Najla M.
Al Gethamy, Manal M.
Alghamdi, Mohammed G.
Rahbeeni, Zuhair A.
Dada, Ashraf
author_facet Alshukairi, Abeer N.
Aldabbagh, Yasser A.
Sayes, Najla M.
Al Gethamy, Manal M.
Alghamdi, Mohammed G.
Rahbeeni, Zuhair A.
Dada, Ashraf
author_sort Alshukairi, Abeer N.
collection PubMed
description Hypogammaglobulinemia is a heterogeneous group of innate and acquired antibody deficiency with variable disease severity, recurrent pneumonia, and bronchiectasis. The outcome of COVID in patients with hypogammaglobulinemia is variable depending on age, comorbidities, type of immunodeficiency, and use of immunoglobulins. We report the favorable outcome of two family members diagnosed with DNAJC17-related retinitis pigmentosa and hypogammaglobulinemia syndrome and infected with SARS-CoV-2 following contact with their mother who had COVID-19. We describe the different immune dysfunction in these patients and their impact on the course and management of SARS-CoV-2 infection.
format Online
Article
Text
id pubmed-8809126
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Wolters Kluwer - Medknow
record_format MEDLINE/PubMed
spelling pubmed-88091262022-02-22 A COVID-19 family cluster with retinitis pigmentosa and hypogammaglobulinemia Alshukairi, Abeer N. Aldabbagh, Yasser A. Sayes, Najla M. Al Gethamy, Manal M. Alghamdi, Mohammed G. Rahbeeni, Zuhair A. Dada, Ashraf Ann Thorac Med Brief Report Hypogammaglobulinemia is a heterogeneous group of innate and acquired antibody deficiency with variable disease severity, recurrent pneumonia, and bronchiectasis. The outcome of COVID in patients with hypogammaglobulinemia is variable depending on age, comorbidities, type of immunodeficiency, and use of immunoglobulins. We report the favorable outcome of two family members diagnosed with DNAJC17-related retinitis pigmentosa and hypogammaglobulinemia syndrome and infected with SARS-CoV-2 following contact with their mother who had COVID-19. We describe the different immune dysfunction in these patients and their impact on the course and management of SARS-CoV-2 infection. Wolters Kluwer - Medknow 2022 2022-01-14 /pmc/articles/PMC8809126/ /pubmed/35198051 http://dx.doi.org/10.4103/atm.atm_520_21 Text en Copyright: © 2022 Annals of Thoracic Medicine https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Brief Report
Alshukairi, Abeer N.
Aldabbagh, Yasser A.
Sayes, Najla M.
Al Gethamy, Manal M.
Alghamdi, Mohammed G.
Rahbeeni, Zuhair A.
Dada, Ashraf
A COVID-19 family cluster with retinitis pigmentosa and hypogammaglobulinemia
title A COVID-19 family cluster with retinitis pigmentosa and hypogammaglobulinemia
title_full A COVID-19 family cluster with retinitis pigmentosa and hypogammaglobulinemia
title_fullStr A COVID-19 family cluster with retinitis pigmentosa and hypogammaglobulinemia
title_full_unstemmed A COVID-19 family cluster with retinitis pigmentosa and hypogammaglobulinemia
title_short A COVID-19 family cluster with retinitis pigmentosa and hypogammaglobulinemia
title_sort covid-19 family cluster with retinitis pigmentosa and hypogammaglobulinemia
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809126/
https://www.ncbi.nlm.nih.gov/pubmed/35198051
http://dx.doi.org/10.4103/atm.atm_520_21
work_keys_str_mv AT alshukairiabeern acovid19familyclusterwithretinitispigmentosaandhypogammaglobulinemia
AT aldabbaghyassera acovid19familyclusterwithretinitispigmentosaandhypogammaglobulinemia
AT sayesnajlam acovid19familyclusterwithretinitispigmentosaandhypogammaglobulinemia
AT algethamymanalm acovid19familyclusterwithretinitispigmentosaandhypogammaglobulinemia
AT alghamdimohammedg acovid19familyclusterwithretinitispigmentosaandhypogammaglobulinemia
AT rahbeenizuhaira acovid19familyclusterwithretinitispigmentosaandhypogammaglobulinemia
AT dadaashraf acovid19familyclusterwithretinitispigmentosaandhypogammaglobulinemia
AT alshukairiabeern covid19familyclusterwithretinitispigmentosaandhypogammaglobulinemia
AT aldabbaghyassera covid19familyclusterwithretinitispigmentosaandhypogammaglobulinemia
AT sayesnajlam covid19familyclusterwithretinitispigmentosaandhypogammaglobulinemia
AT algethamymanalm covid19familyclusterwithretinitispigmentosaandhypogammaglobulinemia
AT alghamdimohammedg covid19familyclusterwithretinitispigmentosaandhypogammaglobulinemia
AT rahbeenizuhaira covid19familyclusterwithretinitispigmentosaandhypogammaglobulinemia
AT dadaashraf covid19familyclusterwithretinitispigmentosaandhypogammaglobulinemia

Ejemplares similares