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Deep sequencing of HIV-1 reveals extensive subtype variation and drug resistance after failure of first-line antiretroviral regimens in Nigeria

BACKGROUND: Deep sequencing could improve understanding of HIV treatment failure and viral population dynamics. However, this tool is often inaccessible in low- and middle-income countries. OBJECTIVES: To determine the genetic patterns of resistance emerging in West African HIV-1 subtypes during fir...

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Detalles Bibliográficos
Autores principales: El Bouzidi, Kate, Datir, Rawlings P., Kwaghe, Vivian, Roy, Sunando, Frampton, Dan, Breuer, Judith, Ogbanufe, Obinna, Murtala-Ibrahim, Fati, Charurat, Man, Dakum, Patrick, Sabin, Caroline A., Ndembi, Nicaise, Gupta, Ravindra K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809188/
https://www.ncbi.nlm.nih.gov/pubmed/34741609
http://dx.doi.org/10.1093/jac/dkab385