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Parallel analysis of transcription, integration, and sequence of single HIV-1 proviruses
HIV-1-infected cells that persist despite antiretroviral therapy (ART) are frequently considered “transcriptionally silent,” but active viral gene expression may occur in some cells, challenging the concept of viral latency. Applying an assay for profiling the transcriptional activity and the chromo...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809251/ https://www.ncbi.nlm.nih.gov/pubmed/35026153 http://dx.doi.org/10.1016/j.cell.2021.12.011 |