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Parallel analysis of transcription, integration, and sequence of single HIV-1 proviruses

HIV-1-infected cells that persist despite antiretroviral therapy (ART) are frequently considered “transcriptionally silent,” but active viral gene expression may occur in some cells, challenging the concept of viral latency. Applying an assay for profiling the transcriptional activity and the chromo...

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Detalles Bibliográficos
Autores principales: Einkauf, Kevin B., Osborn, Matthew R., Gao, Ce, Sun, Weiwei, Sun, Xiaoming, Lian, Xiaodong, Parsons, Elizabeth M., Gladkov, Gregory T., Seiger, Kyra W., Blackmer, Jane E., Jiang, Chenyang, Yukl, Steven A., Rosenberg, Eric S., Yu, Xu G., Lichterfeld, Mathias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809251/
https://www.ncbi.nlm.nih.gov/pubmed/35026153
http://dx.doi.org/10.1016/j.cell.2021.12.011