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Enabling chemical protein (semi)synthesis via reducible solubilizing tags (RSTs)
Chemical synthesis of proteins with poor solubility presents a challenging task. The existing solubilizing tag strategies are not suitable for the expressed protein segment. To address this issue, we report herein that solubilizing tags could be introduced at the side chain of the peptide and C-term...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809390/ https://www.ncbi.nlm.nih.gov/pubmed/35222920 http://dx.doi.org/10.1039/d1sc06387a |