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Asymmetric transformations from sulfoxonium ylides

Sulfoxonium ylides are important surrogates for diazo compounds, and their use in industry as safer alternatives has been evaluated during recent years. Beyond the known classical transformations, these ylides have also been used in a surprising plethora of novel and intrinsic chemical reactions, es...

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Detalles Bibliográficos
Autores principales: Caiuby, Clarice A. D., Furniel, Lucas G., Burtoloso, Antonio C. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809404/
https://www.ncbi.nlm.nih.gov/pubmed/35222906
http://dx.doi.org/10.1039/d1sc05708a
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author Caiuby, Clarice A. D.
Furniel, Lucas G.
Burtoloso, Antonio C. B.
author_facet Caiuby, Clarice A. D.
Furniel, Lucas G.
Burtoloso, Antonio C. B.
author_sort Caiuby, Clarice A. D.
collection PubMed
description Sulfoxonium ylides are important surrogates for diazo compounds, and their use in industry as safer alternatives has been evaluated during recent years. Beyond the known classical transformations, these ylides have also been used in a surprising plethora of novel and intrinsic chemical reactions, especially in recent years. Bench stability and handling are also an advantage of this class of organosulfur molecules. Despite this, efficient asymmetric transformations, specifically catalytic enantioselective versions, have only recently been reported, and there are specific reasons for this. This perspective article covers this topic from the first studies up to the latest advances, giving personal perspectives and showing the main challenges in this area in the coming years.
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spelling pubmed-88094042022-02-24 Asymmetric transformations from sulfoxonium ylides Caiuby, Clarice A. D. Furniel, Lucas G. Burtoloso, Antonio C. B. Chem Sci Chemistry Sulfoxonium ylides are important surrogates for diazo compounds, and their use in industry as safer alternatives has been evaluated during recent years. Beyond the known classical transformations, these ylides have also been used in a surprising plethora of novel and intrinsic chemical reactions, especially in recent years. Bench stability and handling are also an advantage of this class of organosulfur molecules. Despite this, efficient asymmetric transformations, specifically catalytic enantioselective versions, have only recently been reported, and there are specific reasons for this. This perspective article covers this topic from the first studies up to the latest advances, giving personal perspectives and showing the main challenges in this area in the coming years. The Royal Society of Chemistry 2021-12-08 /pmc/articles/PMC8809404/ /pubmed/35222906 http://dx.doi.org/10.1039/d1sc05708a Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Caiuby, Clarice A. D.
Furniel, Lucas G.
Burtoloso, Antonio C. B.
Asymmetric transformations from sulfoxonium ylides
title Asymmetric transformations from sulfoxonium ylides
title_full Asymmetric transformations from sulfoxonium ylides
title_fullStr Asymmetric transformations from sulfoxonium ylides
title_full_unstemmed Asymmetric transformations from sulfoxonium ylides
title_short Asymmetric transformations from sulfoxonium ylides
title_sort asymmetric transformations from sulfoxonium ylides
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809404/
https://www.ncbi.nlm.nih.gov/pubmed/35222906
http://dx.doi.org/10.1039/d1sc05708a
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