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Cytotoxic CD4(+) T cells in cancer: Expanding the immune effector toolbox
Cytotoxic T cells are important effectors of anti-tumor immunity. While tumor killing is ascribed to CD8(+) T cell function, pre-clinical and clinical studies have identified intra-tumoral CD4(+) T cells that possess cytotoxic programs and can directly kill cancer cells. Cytotoxic CD4(+) T cells are...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809482/ https://www.ncbi.nlm.nih.gov/pubmed/34910940 http://dx.doi.org/10.1016/j.immuni.2021.11.015 |