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A yellow fever virus NS4B inhibitor not only suppresses viral replication, but also enhances the virus activation of RIG-I-like receptor-mediated innate immune response

Flavivirus infection of cells induces massive rearrangements of the endoplasmic reticulum (ER) membrane to form viral replication organelles (ROs) which segregates viral RNA replication intermediates from the cytoplasmic RNA sensors. Among other viral nonstructural (NS) proteins, available evidence...

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Detalles Bibliográficos
Autores principales:	Gao, Zhao, Zhang, Xuexiang, Zhang, Lin, Wu, Shuo, Ma, Julia, Wang, Fuxuan, Zhou, Yan, Dai, Xinghong, Bullitt, Esther, Du, Yanming, Guo, Ju-Tao, Chang, Jinhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809586/ https://www.ncbi.nlm.nih.gov/pubmed/35061864 http://dx.doi.org/10.1371/journal.ppat.1010271

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