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cGAS exacerbates Schistosoma japonicum infection in a STING-type I IFN-dependent and independent manner

Schistosomiasis, which is caused by infection with Schistosoma spp., is characterized by granuloma and fibrosis in response to egg deposition. Pattern recognition receptors are important to sense invading Schistosoma, triggering an innate immune response, and subsequently shaping adaptive immunity....

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Detalles Bibliográficos
Autores principales: Liang, Le, Shen, Yujuan, Hu, Yuan, Liu, Haipeng, Cao, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809611/
https://www.ncbi.nlm.nih.gov/pubmed/35108342
http://dx.doi.org/10.1371/journal.ppat.1010233