ERp57/PDIA3: new insight

The ERp57/PDIA3 protein is a pleiotropic member of the PDIs family and, although predominantly located in the endoplasmic reticulum (ER), has indeed been found in other cellular compartments, such as the nucleus or the cell membrane. ERp57/PDIA3 is an important research target considering it can be...

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Autores principales: Chichiarelli, Silvia, Altieri, Fabio, Paglia, Giuliano, Rubini, Elisabetta, Minacori, Marco, Eufemi, Margherita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Invited Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809632/
https://www.ncbi.nlm.nih.gov/pubmed/35109791
http://dx.doi.org/10.1186/s11658-022-00315-x
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author Chichiarelli, Silvia
Altieri, Fabio
Paglia, Giuliano
Rubini, Elisabetta
Minacori, Marco
Eufemi, Margherita
author_facet Chichiarelli, Silvia
Altieri, Fabio
Paglia, Giuliano
Rubini, Elisabetta
Minacori, Marco
Eufemi, Margherita
author_sort Chichiarelli, Silvia
collection PubMed
description The ERp57/PDIA3 protein is a pleiotropic member of the PDIs family and, although predominantly located in the endoplasmic reticulum (ER), has indeed been found in other cellular compartments, such as the nucleus or the cell membrane. ERp57/PDIA3 is an important research target considering it can be found in various subcellular locations. This protein is involved in many different physiological and pathological processes, and our review describes new data on its functions and summarizes some ligands identified as PDIA3-specific inhibitors.
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spelling pubmed-88096322022-02-03 ERp57/PDIA3: new insight Chichiarelli, Silvia Altieri, Fabio Paglia, Giuliano Rubini, Elisabetta Minacori, Marco Eufemi, Margherita Cell Mol Biol Lett Invited Review The ERp57/PDIA3 protein is a pleiotropic member of the PDIs family and, although predominantly located in the endoplasmic reticulum (ER), has indeed been found in other cellular compartments, such as the nucleus or the cell membrane. ERp57/PDIA3 is an important research target considering it can be found in various subcellular locations. This protein is involved in many different physiological and pathological processes, and our review describes new data on its functions and summarizes some ligands identified as PDIA3-specific inhibitors. BioMed Central 2022-02-02 /pmc/articles/PMC8809632/ /pubmed/35109791 http://dx.doi.org/10.1186/s11658-022-00315-x Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Invited Review
Chichiarelli, Silvia
Altieri, Fabio
Paglia, Giuliano
Rubini, Elisabetta
Minacori, Marco
Eufemi, Margherita
ERp57/PDIA3: new insight
title ERp57/PDIA3: new insight
title_full ERp57/PDIA3: new insight
title_fullStr ERp57/PDIA3: new insight
title_full_unstemmed ERp57/PDIA3: new insight
title_short ERp57/PDIA3: new insight
title_sort erp57/pdia3: new insight
topic Invited Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809632/
https://www.ncbi.nlm.nih.gov/pubmed/35109791
http://dx.doi.org/10.1186/s11658-022-00315-x
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