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Naringenin alleviates myocardial ischemia/reperfusion injury by regulating the nuclear factor-erythroid factor 2-related factor 2 (Nrf2) /System xc-/ glutathione peroxidase 4 (GPX4) axis to inhibit ferroptosis

Ferroptosis is an important form of myocardial cell death in myocardial ischemia-reperfusion injury (MIRI). Naringenin (NAR), as a flavonoid, has a significant advantage in improving MIRI. But the regulatory effect and mechanism of NAR on ferroptosis in MIRI have not been reported. After the rats we...

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Detalles Bibliográficos
Autores principales: Xu, Shujun, Wu, Bingxin, Zhong, Biying, Lin, Luoqi, Ding, Yining, Jin, Xiao, Huang, Zhiwei, Lin, Miaoyang, Wu, Huanlin, Xu, Danping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809912/
https://www.ncbi.nlm.nih.gov/pubmed/34699317
http://dx.doi.org/10.1080/21655979.2021.1995994