Cargando…

Naringenin alleviates myocardial ischemia/reperfusion injury by regulating the nuclear factor-erythroid factor 2-related factor 2 (Nrf2) /System xc-/ glutathione peroxidase 4 (GPX4) axis to inhibit ferroptosis

Ferroptosis is an important form of myocardial cell death in myocardial ischemia-reperfusion injury (MIRI). Naringenin (NAR), as a flavonoid, has a significant advantage in improving MIRI. But the regulatory effect and mechanism of NAR on ferroptosis in MIRI have not been reported. After the rats we...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Shujun, Wu, Bingxin, Zhong, Biying, Lin, Luoqi, Ding, Yining, Jin, Xiao, Huang, Zhiwei, Lin, Miaoyang, Wu, Huanlin, Xu, Danping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8809912/ https://www.ncbi.nlm.nih.gov/pubmed/34699317 http://dx.doi.org/10.1080/21655979.2021.1995994

Ejemplares similares

Understanding the Benefits of Standing and Sitting Baduanjin Based on Cardiopulmonary Exercise Testing: An Observational Study
por: Lin, Jinhai, et al.
Publicado: (2021)

Effect of aspirin in takotsubo syndrome: protocol of a systematic review and meta-analysis
por: Lin, Jinhai, et al.
Publicado: (2021)

Homocysteine induces ferroptosis in endothelial cells through the systemXc(−)/GPX4 signaling pathway
por: Shi, Jiahao, et al.
Publicado: (2023)

Correction to: Homocysteine induces ferroptosis in endothelial cells through the systemXc−/GPX4 signaling pathway
por: Shi, Jiahao, et al.
Publicado: (2023)

New alleles of C. elegans gene cls-2 (R107.6), called xc3, xc4, and xc5
por: Munoz, Nicholas R., et al.
Publicado: (2017)

Ferrostatin-1 alleviates tissue and cell damage in diabetic retinopathy by improving the antioxidant capacity of the Xc(-)-GPX4 system
por: Shao, Jingzhi, et al.
Publicado: (2022)

Glutathione peroxidase 4 (Gpx4) and ferroptosis: what's so special about it?
por: Conrad, Marcus, et al.
Publicado: (2015)

Propofol protects cardiomyocytes from doxorubicin-induced toxic injury by activating the nuclear factor erythroid 2-related factor 2/glutathione peroxidase 4 signaling pathways
por: Lu, Ziyun, et al.
Publicado: (2022)

Development of an assay pipeline for the discovery of novel small molecule inhibitors of human glutathione peroxidases GPX1 and GPX4
por: Cheff, Dorian M., et al.
Publicado: (2023)

Impact of Nuclear Factor Erythroid 2–Related Factor 2 in Hepatocellular Carcinoma: Cancer Metabolism and Immune Status
por: Iseda, Norifumi, et al.
Publicado: (2021)

Platycodin D regulates high glucose-induced ferroptosis of HK-2 cells through glutathione peroxidase 4 (GPX4)
por: Huang, Jinzhong, et al.
Publicado: (2022)

Mechanical and Electronic Properties of XC(6) and XC(12)
por: Wei, Qun, et al.
Publicado: (2016)

Naringenin Inhibits Platelet Activation and Arterial Thrombosis Through Inhibition of Phosphoinositide 3-Kinase and Cyclic Nucleotide Signaling
por: Huang, Manting, et al.
Publicado: (2021)

Immunohistochemical Expression of Glutathione Peroxidase 1 (Gpx-1) as an Independent Prognostic Factor in Colon Adenocarcinoma Patients
por: Brzozowa-Zasada, Marlena, et al.
Publicado: (2023)

Immunohistochemical Expression of Glutathione Peroxidase-2 (Gpx-2) and Its Clinical Relevance in Colon Adenocarcinoma Patients
por: Brzozowa-Zasada, Marlena, et al.
Publicado: (2023)

Research progress of glutathione peroxidase family (GPX) in redoxidation
por: Pei, Jun, et al.
Publicado: (2023)

Role of Nuclear Factor Erythroid 2-Related Factor 2 in Diabetic Nephropathy
por: Cui, Wenpeng, et al.
Publicado: (2017)

Nuclear Factor Erythroid 2-Related Factor 2 in Regulating Cancer Metabolism
por: Smolková, Katarína, et al.
Publicado: (2020)

The oxido-reductase enzyme glutathione peroxidase 4 (GPX4) governs Salmonella Typhimurium-induced neutrophil transepithelial migration
por: Agbor, Terence A, et al.
Publicado: (2014)

Sestrin2 Regulates Endoplasmic Reticulum Stress-Dependent Ferroptosis to Engage Pulmonary Fibrosis by Nuclear Factor Erythroid 2-Related Factor 2/Activating Transcription Factor 4 (NRF2/ATF4)
por: Dong, Zhaoxing, et al.
Publicado: (2023)

Extracellular Glutathione Peroxidase GPx3 and Its Role in Cancer
por: Chang, Caroline, et al.
Publicado: (2020)

Glutathione Peroxidase GPX1 and Its Dichotomous Roles in Cancer
por: Zhao, Yangjing, et al.
Publicado: (2022)

Hyperbaric oxygen protects HT22 cells and PC12 cells from damage caused by oxygen-glucose deprivation/reperfusion via the inhibition of Nrf2/System Xc-/GPX4 axis-mediated ferroptosis
por: Chen, Chunxia, et al.
Publicado: (2022)

Physiological Functions of Thiol Peroxidases (Gpx1 and Prdx2) during Xenopus laevis Embryonic Development
por: Lee, Hongchan, et al.
Publicado: (2021)

Identification of Glutathione Peroxidase Gene Family in Ricinus communis and Functional Characterization of RcGPX4 in Cold Tolerance
por: Wang, Xiaoyu, et al.
Publicado: (2021)

Atranorin driven by nano materials SPION lead to ferroptosis of gastric cancer stem cells by weakening the mRNA 5-hydroxymethylcytidine modification of the Xc-/GPX4 axis and its expression
por: Ni, Zhentian, et al.
Publicado: (2022)

The role of nuclear factor erythroid-2-related factor 2 expression in radiocontrast-induced nephropathy
por: Kim, Ji Eun, et al.
Publicado: (2019)

Quinolinic Acid and Nuclear Factor Erythroid 2-Related Factor 2 in Depression: Role in Neuroprogression
por: Bansal, Yashika, et al.
Publicado: (2019)

Nuclear Factor Erythroid-2-Related Factor 2 Signaling in the Neuropathophysiology of Inherited Metabolic Disorders
por: Seminotti, Bianca, et al.
Publicado: (2021)

Role of Nuclear Factor Erythroid 2‒Related Factor 2 in Chronic Obstructive Pulmonary Disease
por: Ban, Woo Ho, et al.
Publicado: (2022)

The nuclear factor erythroid 2-related factor 2/p53 axis in breast cancer
por: Xia, Lei, et al.
Publicado: (2023)

Is Nuclear Factor Erythroid 2-Related Factor 2 a Target for the Intervention of Cytokine Storms?
por: Liu, Zihang, et al.
Publicado: (2023)

Nuclear Factor Erythroid 2 Related Factor 2 Activator JC-5411 Inhibits Atherosclerosis Through Suppression of Inflammation and Regulation of Lipid Metabolism
por: Jiang, Xinhai, et al.
Publicado: (2020)

Glutathione Peroxidase gpx1 to gpx8 Genes Expression in Experimental Brain Tumors Reveals Gender-Dependent Patterns
por: Cueto-Ureña, Cristina, et al.
Publicado: (2023)

Targeted disruption of glutathione peroxidase 4 (GPx4) in mouse skin epithelial cells impairs postnatal hair follicle morphogenesis that is partially rescued through inhibition of COX-2
por: Sengupta, Aniruddha, et al.
Publicado: (2013)

Non-empirical Mixing Coefficient for Hybrid XC Functionals from Analysis of the XC Kernel
por: Moldabekov, Zhandos A., et al.
Publicado: (2023)

Nuclear factor erythroid 2-related factor 2 modulates HER4 receptor in ovarian cancer cells to influence their sensitivity to tyrosine kinase inhibitors
por: Kankia, Ibrahim H., et al.
Publicado: (2021)

New allele of C. elegans gene spch-3 (T27A3.4), called xc2
por: Munoz, Nicholas R., et al.
Publicado: (2018)

Clinicopathological significance of nuclear factor (erythroid-2)-related factor 2 (Nrf2) expression in gastric cancer
por: Kawasaki, Yota, et al.
Publicado: (2015)

Nuclear Factor-Erythroid 2-Related Factor 2 (Nrf2) and Mitochondrial Dynamics/Mitophagy in Neurological Diseases
por: Kang, Tae-Cheon
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_pbuqog2lurdmg6om73kgtiggco