Cargando…

MicroRNA hsa-miR-150-5p inhibits nasopharyngeal carcinogenesis by suppressing PYCR1 (pyrroline-5-carboxylate reductase 1)

Nasopharyngeal cancer is a rare cancer type, but with a low five-year survival rate. Dysregulation of pyrroline-5-carboxylate reductase 1 (PYCR1) and microRNA hsa-miR-150-5p is involved in the development of various cancers. However, the molecular mechanism of the hsa-miR-150-5p-PYCR1 axis in nasoph...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Zhiqun, Zhou, Xiaoliu, Huang, Jiajun, Xu, Zhencai, Xing, Chengliang, Yang, Junwei, Zhou, Xuejun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810012/ https://www.ncbi.nlm.nih.gov/pubmed/34696668 http://dx.doi.org/10.1080/21655979.2021.1995102

Ejemplares similares

Pyrroline-5-carboxylate reductase 1 (PYCR1) upregulation contributes to gastric cancer progression and indicates poor survival outcome
por: Xiao, Shiyu, et al.
Publicado: (2020)

Functional properties and structural characterization of rice δ(1)-pyrroline-5-carboxylate reductase
por: Forlani, Giuseppe, et al.
Publicado: (2015)

Evolution of plant δ(1)-pyrroline-5-carboxylate reductases from phylogenetic and structural perspectives
por: Forlani, Giuseppe, et al.
Publicado: (2015)

Pyrroline-5-Carboxylate Reductase-2 Promotes Colorectal Carcinogenesis by Modulating Microtubule-Associated Serine/Threonine Kinase-like/Wnt/β-Catenin Signaling
por: Lama Tamang, Raju, et al.
Publicado: (2023)

Functional Characterization of Four Putative δ(1)-Pyrroline-5-Carboxylate Reductases from Bacillus subtilis
por: Forlani, Giuseppe, et al.
Publicado: (2017)

Appropriate Activity Assays Are Crucial for the Specific Determination of Proline Dehydrogenase and Pyrroline-5-Carboxylate Reductase Activities
por: Lebreton, Sandrine, et al.
Publicado: (2020)

Pyrroline-5-carboxylate reductase 1 promotes proliferation and inhibits apoptosis in non-small cell lung cancer
por: Cai, Feng, et al.
Publicado: (2018)

Pyrroline-5-carboxylate reductase 1 promotes cell proliferation via inhibiting apoptosis in human malignant melanoma
por: Ye, Yingyi, et al.
Publicado: (2018)

Shikonin induces apoptosis and autophagy via downregulation of pyrroline-5-carboxylate reductase1 in hepatocellular carcinoma cells
por: Zhang, Junli, et al.
Publicado: (2022)

Functional Impact of a Cancer-Related Variant in Human Δ(1)-Pyrroline-5-Carboxylate Reductase 1
por: Daudu, Oseeyi I., et al.
Publicado: (2023)

Pyrroline-5-carboxylate reductase 1 reprograms proline metabolism to drive breast cancer stemness under psychological stress
por: Cui, Bai, et al.
Publicado: (2023)

The structure of Medicago truncatula δ(1)-pyrroline-5-carboxylate reductase provides new insights into regulation of proline biosynthesis in plants
por: Ruszkowski, Milosz, et al.
Publicado: (2015)

Preparation of Phosphonic Acid Analogues of Proline and Proline Analogues and Their Biological Evaluation as δ(1)-Pyrroline-5-carboxylate Reductase Inhibitors
por: Qian, Renzhe, et al.
Publicado: (2018)

Δ(1)-Pyrroline-5-Carboxylate/Glutamate Biogenesis Is Required for Fungal Virulence and Sporulation
por: Yao, Ziting, et al.
Publicado: (2013)

Pyrroline-5-Carboxylate Reductase 1 Directs the Cartilage Protective and Regenerative Potential of Murphy Roths Large Mouse Mesenchymal Stem Cells
por: Tejedor, Gautier, et al.
Publicado: (2021)

Pyrroline-5-Carboxylate Reductase-2 Promotes Colorectal Cancer Progression via Activating PI3K/AKT/mTOR Pathway
por: Yin, Feng, et al.
Publicado: (2021)

Role of proline and pyrroline-5-carboxylate metabolism in plant defense against invading pathogens
por: Qamar, Aarzoo, et al.
Publicado: (2015)

Enzymology and Regulation of δ(1)-Pyrroline-5-Carboxylate Synthetase 2 From Rice
por: Sabbioni, Giuseppe, et al.
Publicado: (2021)

Identification of Δ-1-pyrroline-5-carboxylate derived biomarkers for hyperprolinemia type II
por: Merx, Jona, et al.
Publicado: (2022)

Pyrroline-5-Carboxylate Reductase 1: a novel target for sensitizing multiple myeloma cells to bortezomib by inhibition of PRAS40-mediated protein synthesis
por: Oudaert, Inge, et al.
Publicado: (2022)

Proline Dehydrogenase and Pyrroline 5 Carboxylate Dehydrogenase from Mycobacterium tuberculosis: Evidence for Substrate Channeling
por: Kumar, Santosh, et al.
Publicado: (2023)

LINC00511 aggravates the malignancy of lung adenocarcinoma through sponging microRNA miR‐4739 to regulate pyrroline‐5‐carboxylate reductase 1 expression
por: Ye, Lu, et al.
Publicado: (2022)

Celastrol Combats Methicillin‐Resistant Staphylococcus aureus by Targeting Δ(1)‐Pyrroline‐5‐Carboxylate Dehydrogenase
por: Yuan, Zhongwei, et al.
Publicado: (2023)

Biphenyl-4,4′-diyl bis(2,2,5,5-tetramethyl-1-oxyl-3-pyrroline-3-carboxylate)
por: Margraf, Dominik, et al.
Publicado: (2009)

150 Carcinogenesis of HPV
por: Buonaguro, FM, et al.
Publicado: (2014)

The Δ1-pyrroline-5-carboxylate synthetase family performs diverse physiological functions in stress responses in pear (Pyrus betulifolia)
por: Ma, Changqing, et al.
Publicado: (2022)

Simplified Synthesis of Isotopically Labeled 5,5-Dimethyl-pyrroline N-Oxide
por: Leinisch, Fabian, et al.
Publicado: (2011)

PYCR1 and PYCR2 Interact and Collaborate with RRM2B to Protect Cells from Overt Oxidative Stress
por: Kuo, Mei-Ling, et al.
Publicado: (2016)

Structural Studies of Yeast Δ(1)-Pyrroline-5-carboxylate Dehydrogenase (ALDH4A1): Active Site Flexibility and Oligomeric State
por: Pemberton, Travis A., et al.
Publicado: (2014)

Functional characterization and expression analysis of rice δ(1)-pyrroline-5-carboxylate dehydrogenase provide new insight into the regulation of proline and arginine catabolism
por: Forlani, Giuseppe, et al.
Publicado: (2015)

3-Ethynyl-2,2,5,5-tetramethyl-1-oxyl-3-pyrroline
por: Frolow, Olga, et al.
Publicado: (2009)

Identification and characterization of trans-3-hydroxy-l-proline dehydratase and Δ(1)-pyrroline-2-carboxylate reductase involved in trans-3-hydroxy-l-proline metabolism of bacteria
por: Watanabe, Seiya, et al.
Publicado: (2014)

4,4′,4′′-(Methanetriyl)triphenyl tris(2,2,5,5-tetramethyl-1-oxyl-3-pyrroline-3-carboxylate) benzene trisolvate
por: Schuetz, Denise, et al.
Publicado: (2010)

1-Pyrroline-5-carboxylate released by prostate Cancer cell inhibit T cell proliferation and function by targeting SHP1/cytochrome c oxidoreductase/ROS Axis
por: Yan, Yutao, et al.
Publicado: (2018)

Metabolomic and transcriptomic studies of improvements in myocardial infarction due to Pycr1 deletion
por: Xue, Zhimin, et al.
Publicado: (2022)

Survival and clinicopathological significance of PYCR1 expression in cancer: A meta-analysis
por: Li, Yue, et al.
Publicado: (2022)

Overexpression of the Lolium perenne L. delta1-pyrroline 5-carboxylate synthase (LpP5CS) gene results in morphological alterations and salinity tolerance in switchgrass (Panicum virgatum L.)
por: Guan, Cong, et al.
Publicado: (2019)

Metal-mediated synthesis of pyrrolines
por: Medran, Noelia S., et al.
Publicado: (2019)

PYCR1 is Associated with Papillary Renal Cell Carcinoma Progression
por: Wang, Qiu-Li, et al.
Publicado: (2019)

The clinical significance of PYCR1 expression in renal cell carcinoma
por: Weijin, Fu, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_3cran4gtioocmin6p5hjtoh8o9