RUNX1 (RUNX family transcription factor 1), a target of microRNA miR-128-3p, promotes temozolomide resistance in glioblastoma multiform by upregulating multidrug resistance-associated protein 1 (MRP1)

Glioblastoma multiform (GBM) is the most frequent type of malignant brain tumor with a poor prognosis. After optimal surgery, radiotherapy plus temozolomide (TMZ) is the standard treatment for GBM patients. However, the development of TMZ resistance limits its efficacy in GBM management. Runt Relate...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Jianglong, Song, Jia, Xiao, Menglin, Wang, Changsheng, Zhang, Qisong, Yuan, Xiaoye, Tian, Shaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810036/
https://www.ncbi.nlm.nih.gov/pubmed/34895074
http://dx.doi.org/10.1080/21655979.2021.2009976

Ejemplares similares

Ejemplares similares