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Engineered mRNA-expressed bispecific antibody prevent intestinal cancer via lipid nanoparticle delivery
The potential of antibodies, especially for the bispecific antibodies, are limited by high cost and complex technical process of development and manufacturing. A cost-effective and rapid platform for the endogenous antibodies expression via using the in vitro transcription (IVT) technique to produce...
Autores principales: | Wu, Lipei, Wang, Weiwei, Tian, Jiale, Qi, Chunrun, Cai, Zhengxin, Yan, Wenhui, Xuan, Shihai, Shang, Anquan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810065/ https://www.ncbi.nlm.nih.gov/pubmed/34895063 http://dx.doi.org/10.1080/21655979.2021.2003666 |
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