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DNA methyltransferase 3 beta mediates the methylation of the microRNA-34a promoter and enhances chondrocyte viability in osteoarthritis

Osteoarthritis (OA) is characterized by destruction of articular cartilage with an imbalance between synthesis and degradation of extracellular matrix (ECM). In the current study, we explored the role of microRNA-34a (miR-34a) and the behind epigenetic mechanism in the degradation of ECM in OA. Usin...

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Detalles Bibliográficos
Autores principales:	Xiong, Shouliang, Zhao, Yong, Xu, Tiantong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810119/ https://www.ncbi.nlm.nih.gov/pubmed/34783292 http://dx.doi.org/10.1080/21655979.2021.2005308

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