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Isoliquiritigenin attenuates acute renal injury through suppressing oxidative stress, fibrosis and JAK2/STAT3 pathway in streptozotocin-induced diabetic rats

The aim of the current study was to evaluate the protective effects and mechanisms of isoliquiritigenin (ISO) on acute renal injury. CCK-8 assays were applied to assess the effects of ISO at different doses (20, 40, and 80 μg/mL) on oxidative damage in human renal HK-2 cells incubated with high gluc...

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Detalles Bibliográficos
Autores principales: Sun, Leiming, Yang, Zheng, Zhang, Jiaying, Wang, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810184/
https://www.ncbi.nlm.nih.gov/pubmed/34784849
http://dx.doi.org/10.1080/21655979.2021.2006978

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