Cargando…
De novo design of CRISPR-Cas13b enables efficient silencing of SARS-CoV-2 variants and tumour pathogenic RNAs with near single-base precision
Autores principales: | Hu, Wenxin, Zhao, Wei, Kumar, Amit, Singh, Gurjeet Jagjeet, Qi, Shijiao, Casan, Josh, Shembery, Carolyn, Fong, Danielle, Zerbato, Jennifer M., Symons, Jori, Rudraraju, Rajeev, Purcell, Damian, Haber, Michelle, Voskoboinik, Ilia, Ekert, Paul G., Lewin, Sharon, Trapani, Joseph, Fareh, Mohamed |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier B.V.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810216/ http://dx.doi.org/10.1016/j.pathol.2021.12.057 |
Ejemplares similares
-
Reprogrammed CRISPR-Cas13b suppresses SARS-CoV-2 replication and circumvents its mutational escape through mismatch tolerance
por: Fareh, Mohamed, et al.
Publicado: (2021) -
Perforinopathy: A Spectrum of Human Immune Disease Caused by Defective Perforin Delivery or Function
por: Voskoboinik, Ilia, et al.
Publicado: (2013) -
Lipid specificity of the immune effector perforin
por: Hodel, Adrian W., et al.
Publicado: (2020) -
B cell-derived circulating granzyme B is a feature of acute infectious mononucleosis
por: Hagn, Magdalena, et al.
Publicado: (2015) -
The pore conformation of lymphocyte perforin
por: Ivanova, Marina E., et al.
Publicado: (2022)