Trousseau's Syndrome Presenting as Multiple Cerebral Infarctions Caused by Mucin-producing Bladder Micropapillary Urothelial Cancer

We herein report a 70-year-old man with recurrent multiple cerebral infarctions under warfarin therapy who was finally diagnosed with Trousseau's syndrome resulting from advanced bladder cancer. A histological examination of the mesenteric lymph nodes revealed metastasis of micropapillary uroth...

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Autores principales: Shimohama, Sho, Oki, Koichi, Narita, Hidefumi, Mashima, Kyoko, Yamada, Satoshi, Adachi, Tomohide, Kobayashi, Yosuke, Hirose, Shigemichi, Hoshino, Haruhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810238/
https://www.ncbi.nlm.nih.gov/pubmed/34176838
http://dx.doi.org/10.2169/internalmedicine.7477-21
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author Shimohama, Sho
Oki, Koichi
Narita, Hidefumi
Mashima, Kyoko
Yamada, Satoshi
Adachi, Tomohide
Kobayashi, Yosuke
Hirose, Shigemichi
Hoshino, Haruhiko
author_facet Shimohama, Sho
Oki, Koichi
Narita, Hidefumi
Mashima, Kyoko
Yamada, Satoshi
Adachi, Tomohide
Kobayashi, Yosuke
Hirose, Shigemichi
Hoshino, Haruhiko
author_sort Shimohama, Sho
collection PubMed
description We herein report a 70-year-old man with recurrent multiple cerebral infarctions under warfarin therapy who was finally diagnosed with Trousseau's syndrome resulting from advanced bladder cancer. A histological examination of the mesenteric lymph nodes revealed metastasis of micropapillary urothelial cancer with positive mucin markers CA125 and MUC1. Blood examinations also indicated elevated tumor markers, such as CA19-9 and CA125. To our knowledge, this is the first report of Trousseau's syndrome in a patient with bladder micropapillary urothelial cancer in which mucin involvement was clearly proven by histological and serological examinations.
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spelling pubmed-88102382022-02-15 Trousseau's Syndrome Presenting as Multiple Cerebral Infarctions Caused by Mucin-producing Bladder Micropapillary Urothelial Cancer Shimohama, Sho Oki, Koichi Narita, Hidefumi Mashima, Kyoko Yamada, Satoshi Adachi, Tomohide Kobayashi, Yosuke Hirose, Shigemichi Hoshino, Haruhiko Intern Med Case Report We herein report a 70-year-old man with recurrent multiple cerebral infarctions under warfarin therapy who was finally diagnosed with Trousseau's syndrome resulting from advanced bladder cancer. A histological examination of the mesenteric lymph nodes revealed metastasis of micropapillary urothelial cancer with positive mucin markers CA125 and MUC1. Blood examinations also indicated elevated tumor markers, such as CA19-9 and CA125. To our knowledge, this is the first report of Trousseau's syndrome in a patient with bladder micropapillary urothelial cancer in which mucin involvement was clearly proven by histological and serological examinations. The Japanese Society of Internal Medicine 2021-06-26 2022-01-01 /pmc/articles/PMC8810238/ /pubmed/34176838 http://dx.doi.org/10.2169/internalmedicine.7477-21 Text en Copyright © 2022 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Shimohama, Sho
Oki, Koichi
Narita, Hidefumi
Mashima, Kyoko
Yamada, Satoshi
Adachi, Tomohide
Kobayashi, Yosuke
Hirose, Shigemichi
Hoshino, Haruhiko
Trousseau's Syndrome Presenting as Multiple Cerebral Infarctions Caused by Mucin-producing Bladder Micropapillary Urothelial Cancer
title Trousseau's Syndrome Presenting as Multiple Cerebral Infarctions Caused by Mucin-producing Bladder Micropapillary Urothelial Cancer
title_full Trousseau's Syndrome Presenting as Multiple Cerebral Infarctions Caused by Mucin-producing Bladder Micropapillary Urothelial Cancer
title_fullStr Trousseau's Syndrome Presenting as Multiple Cerebral Infarctions Caused by Mucin-producing Bladder Micropapillary Urothelial Cancer
title_full_unstemmed Trousseau's Syndrome Presenting as Multiple Cerebral Infarctions Caused by Mucin-producing Bladder Micropapillary Urothelial Cancer
title_short Trousseau's Syndrome Presenting as Multiple Cerebral Infarctions Caused by Mucin-producing Bladder Micropapillary Urothelial Cancer
title_sort trousseau's syndrome presenting as multiple cerebral infarctions caused by mucin-producing bladder micropapillary urothelial cancer
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810238/
https://www.ncbi.nlm.nih.gov/pubmed/34176838
http://dx.doi.org/10.2169/internalmedicine.7477-21
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