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Remission of Angiographically Confirmed Minocycline-induced Renal Polyarteritis Nodosa: A Case Report and Literature Review
A 23-year-old man presented with severe hypertension. Based on his history of minocycline treatment for over three years and clinical symptoms, such as myalgias and renovascular hypertension with multiple intrarenal aneurysms, he was diagnosed with minocycline-induced renal polyarteritis nodosa (PAN...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society of Internal Medicine
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810245/ https://www.ncbi.nlm.nih.gov/pubmed/34176836 http://dx.doi.org/10.2169/internalmedicine.7340-21 |
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author | Yokota, Kenichi Kurihara, Isao Nakamura, Toshifumi Nakatsuka, Seishi Miyashita, Kazutoshi Kobayashi, Sakiko Murai-Takeda, Ayano Sone, Masakatsu Itoh, Hiroshi |
author_facet | Yokota, Kenichi Kurihara, Isao Nakamura, Toshifumi Nakatsuka, Seishi Miyashita, Kazutoshi Kobayashi, Sakiko Murai-Takeda, Ayano Sone, Masakatsu Itoh, Hiroshi |
author_sort | Yokota, Kenichi |
collection | PubMed |
description | A 23-year-old man presented with severe hypertension. Based on his history of minocycline treatment for over three years and clinical symptoms, such as myalgias and renovascular hypertension with multiple intrarenal aneurysms, he was diagnosed with minocycline-induced renal polyarteritis nodosa (PAN). After minocycline treatment cessation and management of the hypertension, his blood pressure, renin-aldosterone levels, and urinary protein levels gradually improved. Seven and a half years later, repeated angiography found that the aneurysms had resolved. This is the first report in English describing a case of minocycline-induced renal PAN that was reversed functionally and morphologically without steroids or immunosuppressive drugs. |
format | Online Article Text |
id | pubmed-8810245 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Japanese Society of Internal Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-88102452022-02-15 Remission of Angiographically Confirmed Minocycline-induced Renal Polyarteritis Nodosa: A Case Report and Literature Review Yokota, Kenichi Kurihara, Isao Nakamura, Toshifumi Nakatsuka, Seishi Miyashita, Kazutoshi Kobayashi, Sakiko Murai-Takeda, Ayano Sone, Masakatsu Itoh, Hiroshi Intern Med Case Report A 23-year-old man presented with severe hypertension. Based on his history of minocycline treatment for over three years and clinical symptoms, such as myalgias and renovascular hypertension with multiple intrarenal aneurysms, he was diagnosed with minocycline-induced renal polyarteritis nodosa (PAN). After minocycline treatment cessation and management of the hypertension, his blood pressure, renin-aldosterone levels, and urinary protein levels gradually improved. Seven and a half years later, repeated angiography found that the aneurysms had resolved. This is the first report in English describing a case of minocycline-induced renal PAN that was reversed functionally and morphologically without steroids or immunosuppressive drugs. The Japanese Society of Internal Medicine 2021-06-26 2022-01-01 /pmc/articles/PMC8810245/ /pubmed/34176836 http://dx.doi.org/10.2169/internalmedicine.7340-21 Text en Copyright © 2022 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Yokota, Kenichi Kurihara, Isao Nakamura, Toshifumi Nakatsuka, Seishi Miyashita, Kazutoshi Kobayashi, Sakiko Murai-Takeda, Ayano Sone, Masakatsu Itoh, Hiroshi Remission of Angiographically Confirmed Minocycline-induced Renal Polyarteritis Nodosa: A Case Report and Literature Review |
title | Remission of Angiographically Confirmed Minocycline-induced Renal Polyarteritis Nodosa: A Case Report and Literature Review |
title_full | Remission of Angiographically Confirmed Minocycline-induced Renal Polyarteritis Nodosa: A Case Report and Literature Review |
title_fullStr | Remission of Angiographically Confirmed Minocycline-induced Renal Polyarteritis Nodosa: A Case Report and Literature Review |
title_full_unstemmed | Remission of Angiographically Confirmed Minocycline-induced Renal Polyarteritis Nodosa: A Case Report and Literature Review |
title_short | Remission of Angiographically Confirmed Minocycline-induced Renal Polyarteritis Nodosa: A Case Report and Literature Review |
title_sort | remission of angiographically confirmed minocycline-induced renal polyarteritis nodosa: a case report and literature review |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810245/ https://www.ncbi.nlm.nih.gov/pubmed/34176836 http://dx.doi.org/10.2169/internalmedicine.7340-21 |
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