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Adverse Effects of Kampo Medicines

This review summarizes the adverse effects of Kampo medicines. These adverse effects in terms of immunoallergic reactions include interstitial pneumonia, liver injury, allergic cystitis, and drug eruption. Many cases of interstitial pneumonia, liver injury, and allergic cystitis associated with Kamp...

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Autor principal: Shimada, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810258/
https://www.ncbi.nlm.nih.gov/pubmed/33551404
http://dx.doi.org/10.2169/internalmedicine.6292-20
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author Shimada, Yutaka
author_facet Shimada, Yutaka
author_sort Shimada, Yutaka
collection PubMed
description This review summarizes the adverse effects of Kampo medicines. These adverse effects in terms of immunoallergic reactions include interstitial pneumonia, liver injury, allergic cystitis, and drug eruption. Many cases of interstitial pneumonia, liver injury, and allergic cystitis associated with Kampo formulas have been reported to be caused by formulas containing Scutellariae Radix (Scutellaria root, ogon). The known adverse effects linked to overdose of Kampo formulas include pseudoaldosteronism [caused by Glycyrrhizae Radix (licorice, kanzo)], sympathomimetic symptoms [caused by Ephedrae Herba (ephedra, mao)], aconite poisoning [caused by Aconiti Tuber (processed aconite root, bushi and uzu)], and diarrhea [caused by Rhei Rhizoma (rhubarb, daio)]. In recent years, mesenteric phlebosclerosis caused by the long-term administration of Gardeniae Fructus (gardenia fruit, sanshishi) has also been reported. It is necessary to consider these potential adverse effects when prescribing Kampo medicines in clinical practice.
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spelling pubmed-88102582022-02-15 Adverse Effects of Kampo Medicines Shimada, Yutaka Intern Med Review Article This review summarizes the adverse effects of Kampo medicines. These adverse effects in terms of immunoallergic reactions include interstitial pneumonia, liver injury, allergic cystitis, and drug eruption. Many cases of interstitial pneumonia, liver injury, and allergic cystitis associated with Kampo formulas have been reported to be caused by formulas containing Scutellariae Radix (Scutellaria root, ogon). The known adverse effects linked to overdose of Kampo formulas include pseudoaldosteronism [caused by Glycyrrhizae Radix (licorice, kanzo)], sympathomimetic symptoms [caused by Ephedrae Herba (ephedra, mao)], aconite poisoning [caused by Aconiti Tuber (processed aconite root, bushi and uzu)], and diarrhea [caused by Rhei Rhizoma (rhubarb, daio)]. In recent years, mesenteric phlebosclerosis caused by the long-term administration of Gardeniae Fructus (gardenia fruit, sanshishi) has also been reported. It is necessary to consider these potential adverse effects when prescribing Kampo medicines in clinical practice. The Japanese Society of Internal Medicine 2021-02-08 2022-01-01 /pmc/articles/PMC8810258/ /pubmed/33551404 http://dx.doi.org/10.2169/internalmedicine.6292-20 Text en Copyright © 2022 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Article
Shimada, Yutaka
Adverse Effects of Kampo Medicines
title Adverse Effects of Kampo Medicines
title_full Adverse Effects of Kampo Medicines
title_fullStr Adverse Effects of Kampo Medicines
title_full_unstemmed Adverse Effects of Kampo Medicines
title_short Adverse Effects of Kampo Medicines
title_sort adverse effects of kampo medicines
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810258/
https://www.ncbi.nlm.nih.gov/pubmed/33551404
http://dx.doi.org/10.2169/internalmedicine.6292-20
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