Severe Hypomagnesemia Associated with the Long-term Use of the Potassium-competitive Acid Blocker Vonoprazan

Hypomagnesemia caused by a proton pump inhibitor (PPI) was first reported in 2006. We herein report a case of hypomagnesemia due to the long-term use of vonoprazan, a potassium-competitive acid blocker (P-CAB). A 66-year-old man was admitted to our hospital complaining of disturbance of consciousnes...

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Autores principales: Okamoto, Masaru, Wakunami, Yu, Hashimoto, Kyoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810260/
https://www.ncbi.nlm.nih.gov/pubmed/34176835
http://dx.doi.org/10.2169/internalmedicine.7325-21
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author Okamoto, Masaru
Wakunami, Yu
Hashimoto, Kyoji
author_facet Okamoto, Masaru
Wakunami, Yu
Hashimoto, Kyoji
author_sort Okamoto, Masaru
collection PubMed
description Hypomagnesemia caused by a proton pump inhibitor (PPI) was first reported in 2006. We herein report a case of hypomagnesemia due to the long-term use of vonoprazan, a potassium-competitive acid blocker (P-CAB). A 66-year-old man was admitted to our hospital complaining of disturbance of consciousness with evidence of hypomagnesemia noted on blood testing. The long-term use of vonoprazan was considered the cause of his hypomagnesemia, so it was discontinued, after which the hypomagnesemia improved. Hypomagnesemia can be induced not only by PPI treatment but also following the long-term use of P-CAB.
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spelling pubmed-88102602022-02-15 Severe Hypomagnesemia Associated with the Long-term Use of the Potassium-competitive Acid Blocker Vonoprazan Okamoto, Masaru Wakunami, Yu Hashimoto, Kyoji Intern Med Case Report Hypomagnesemia caused by a proton pump inhibitor (PPI) was first reported in 2006. We herein report a case of hypomagnesemia due to the long-term use of vonoprazan, a potassium-competitive acid blocker (P-CAB). A 66-year-old man was admitted to our hospital complaining of disturbance of consciousness with evidence of hypomagnesemia noted on blood testing. The long-term use of vonoprazan was considered the cause of his hypomagnesemia, so it was discontinued, after which the hypomagnesemia improved. Hypomagnesemia can be induced not only by PPI treatment but also following the long-term use of P-CAB. The Japanese Society of Internal Medicine 2021-06-26 2022-01-01 /pmc/articles/PMC8810260/ /pubmed/34176835 http://dx.doi.org/10.2169/internalmedicine.7325-21 Text en Copyright © 2022 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Okamoto, Masaru
Wakunami, Yu
Hashimoto, Kyoji
Severe Hypomagnesemia Associated with the Long-term Use of the Potassium-competitive Acid Blocker Vonoprazan
title Severe Hypomagnesemia Associated with the Long-term Use of the Potassium-competitive Acid Blocker Vonoprazan
title_full Severe Hypomagnesemia Associated with the Long-term Use of the Potassium-competitive Acid Blocker Vonoprazan
title_fullStr Severe Hypomagnesemia Associated with the Long-term Use of the Potassium-competitive Acid Blocker Vonoprazan
title_full_unstemmed Severe Hypomagnesemia Associated with the Long-term Use of the Potassium-competitive Acid Blocker Vonoprazan
title_short Severe Hypomagnesemia Associated with the Long-term Use of the Potassium-competitive Acid Blocker Vonoprazan
title_sort severe hypomagnesemia associated with the long-term use of the potassium-competitive acid blocker vonoprazan
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810260/
https://www.ncbi.nlm.nih.gov/pubmed/34176835
http://dx.doi.org/10.2169/internalmedicine.7325-21
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AT hashimotokyoji severehypomagnesemiaassociatedwiththelongtermuseofthepotassiumcompetitiveacidblockervonoprazan

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