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Emergence of methicillin resistance predates the clinical use of antibiotics

The discovery of antibiotics more than 80 years ago has led to considerable improvements in human and animal health. Although antibiotic resistance in environmental bacteria is ancient, resistance in human pathogens is thought to be a modern phenomenon that is driven by the clinical use of antibioti...

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Autores principales: Larsen, Jesper, Raisen, Claire L., Ba, Xiaoliang, Sadgrove, Nicholas J., Padilla-González, Guillermo F., Simmonds, Monique S. J., Loncaric, Igor, Kerschner, Heidrun, Apfalter, Petra, Hartl, Rainer, Deplano, Ariane, Vandendriessche, Stien, Černá Bolfíková, Barbora, Hulva, Pavel, Arendrup, Maiken C., Hare, Rasmus K., Barnadas, Céline, Stegger, Marc, Sieber, Raphael N., Skov, Robert L., Petersen, Andreas, Angen, Øystein, Rasmussen, Sophie L., Espinosa-Gongora, Carmen, Aarestrup, Frank M., Lindholm, Laura J., Nykäsenoja, Suvi M., Laurent, Frederic, Becker, Karsten, Walther, Birgit, Kehrenberg, Corinna, Cuny, Christiane, Layer, Franziska, Werner, Guido, Witte, Wolfgang, Stamm, Ivonne, Moroni, Paolo, Jørgensen, Hannah J., de Lencastre, Hermínia, Cercenado, Emilia, García-Garrote, Fernando, Börjesson, Stefan, Hæggman, Sara, Perreten, Vincent, Teale, Christopher J., Waller, Andrew S., Pichon, Bruno, Curran, Martin D., Ellington, Matthew J., Welch, John J., Peacock, Sharon J., Seilly, David J., Morgan, Fiona J. E., Parkhill, Julian, Hadjirin, Nazreen F., Lindsay, Jodi A., Holden, Matthew T. G., Edwards, Giles F., Foster, Geoffrey, Paterson, Gavin K., Didelot, Xavier, Holmes, Mark A., Harrison, Ewan M., Larsen, Anders R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810379/
https://www.ncbi.nlm.nih.gov/pubmed/34987223
http://dx.doi.org/10.1038/s41586-021-04265-w