Clinical aspects and presumed etiology of multisystem inflammatory syndrome in children (MIS-C): A review

The COVID-19 outbreak sparked by SARS-CoV-2, begat significant rates of malady worldwide, where children with an abnormal post-COVID ailment called the Multisystem Inflammatory Syndrome (MIS-C), were reported by April 2020. Here we have reviewed the clinical characteristics of the pediatric patients...

Descripción completa

Detalles Bibliográficos
Autores principales: Kundu, Anusrita, Maji, Swagata, Kumar, Suchismita, Bhattacharya, Shreya, Chakraborty, Pallab, Sarkar, Joy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier B.V. on behalf of INDIACLEN. 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810427/
https://www.ncbi.nlm.nih.gov/pubmed/35132389
http://dx.doi.org/10.1016/j.cegh.2022.100966
_version_ 1784644252845735936
author Kundu, Anusrita
Maji, Swagata
Kumar, Suchismita
Bhattacharya, Shreya
Chakraborty, Pallab
Sarkar, Joy
author_facet Kundu, Anusrita
Maji, Swagata
Kumar, Suchismita
Bhattacharya, Shreya
Chakraborty, Pallab
Sarkar, Joy
author_sort Kundu, Anusrita
collection PubMed
description The COVID-19 outbreak sparked by SARS-CoV-2, begat significant rates of malady worldwide, where children with an abnormal post-COVID ailment called the Multisystem Inflammatory Syndrome (MIS-C), were reported by April 2020. Here we have reviewed the clinical characteristics of the pediatric patients and the prognosis currently being utilized. A vivid comparison of MIS-C with other clinical conditions has been done. We have addressed the probable etiology and fundamental machinery of the inflammatory reactions, which drive organ failure. The involvement of androgen receptors portrays the likelihood of asymptomatic illness in children below adolescence, contributing to the concept of antibody-dependent enhancement.
format Online
Article
Text
id pubmed-8810427
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher The Author(s). Published by Elsevier B.V. on behalf of INDIACLEN.
record_format MEDLINE/PubMed
spelling pubmed-88104272022-02-03 Clinical aspects and presumed etiology of multisystem inflammatory syndrome in children (MIS-C): A review Kundu, Anusrita Maji, Swagata Kumar, Suchismita Bhattacharya, Shreya Chakraborty, Pallab Sarkar, Joy Clin Epidemiol Glob Health Review Article The COVID-19 outbreak sparked by SARS-CoV-2, begat significant rates of malady worldwide, where children with an abnormal post-COVID ailment called the Multisystem Inflammatory Syndrome (MIS-C), were reported by April 2020. Here we have reviewed the clinical characteristics of the pediatric patients and the prognosis currently being utilized. A vivid comparison of MIS-C with other clinical conditions has been done. We have addressed the probable etiology and fundamental machinery of the inflammatory reactions, which drive organ failure. The involvement of androgen receptors portrays the likelihood of asymptomatic illness in children below adolescence, contributing to the concept of antibody-dependent enhancement. The Author(s). Published by Elsevier B.V. on behalf of INDIACLEN. 2022 2022-02-03 /pmc/articles/PMC8810427/ /pubmed/35132389 http://dx.doi.org/10.1016/j.cegh.2022.100966 Text en © 2022 The Author(s) Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Review Article
Kundu, Anusrita
Maji, Swagata
Kumar, Suchismita
Bhattacharya, Shreya
Chakraborty, Pallab
Sarkar, Joy
Clinical aspects and presumed etiology of multisystem inflammatory syndrome in children (MIS-C): A review
title Clinical aspects and presumed etiology of multisystem inflammatory syndrome in children (MIS-C): A review
title_full Clinical aspects and presumed etiology of multisystem inflammatory syndrome in children (MIS-C): A review
title_fullStr Clinical aspects and presumed etiology of multisystem inflammatory syndrome in children (MIS-C): A review
title_full_unstemmed Clinical aspects and presumed etiology of multisystem inflammatory syndrome in children (MIS-C): A review
title_short Clinical aspects and presumed etiology of multisystem inflammatory syndrome in children (MIS-C): A review
title_sort clinical aspects and presumed etiology of multisystem inflammatory syndrome in children (mis-c): a review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810427/
https://www.ncbi.nlm.nih.gov/pubmed/35132389
http://dx.doi.org/10.1016/j.cegh.2022.100966
work_keys_str_mv AT kunduanusrita clinicalaspectsandpresumedetiologyofmultisysteminflammatorysyndromeinchildrenmiscareview
AT majiswagata clinicalaspectsandpresumedetiologyofmultisysteminflammatorysyndromeinchildrenmiscareview
AT kumarsuchismita clinicalaspectsandpresumedetiologyofmultisysteminflammatorysyndromeinchildrenmiscareview
AT bhattacharyashreya clinicalaspectsandpresumedetiologyofmultisysteminflammatorysyndromeinchildrenmiscareview
AT chakrabortypallab clinicalaspectsandpresumedetiologyofmultisysteminflammatorysyndromeinchildrenmiscareview
AT sarkarjoy clinicalaspectsandpresumedetiologyofmultisysteminflammatorysyndromeinchildrenmiscareview

Ejemplares similares