Deletion of Six3 in post-proliferative neurons produces weakened SCN circadian output, improved metabolic function, and dwarfism in male mice

OBJECTIVE: The increasing prevalence of obesity makes it important to increase the understanding of the maturation and function of the neuronal integrators and regulators of metabolic function. METHODS: Behavioral, molecular, and physiological analyses of transgenic mice with Sine oculis 3 (Six3) de...

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Detalles Bibliográficos
Autores principales: Meadows, Jason D., Breuer, Joseph A., Lavalle, Shanna N., Hirschenberger, Michael R., Patel, Meera M., Nguyen, Duong, Kim, Alyssa, Cassin, Jessica, Gorman, Michael R., Welsh, David K., Mellon, Pamela L., Hoffmann, Hanne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810556/
https://www.ncbi.nlm.nih.gov/pubmed/34974160
http://dx.doi.org/10.1016/j.molmet.2021.101431

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